Shandong Provincial Center for Disease Control and Prevention, Jinan, Shandong, China.
Chinese Field Epidemiology Training Program, Chinese Center for Disease Control and Prevention, Beijing, China.
BMC Infect Dis. 2022 Nov 22;22(1):875. doi: 10.1186/s12879-022-07802-8.
In order to verify the existence of an anthrax outbreak, determine its scope, grasp the epidemiological characteristics and find out the cause of the outbreak and recommend preventive and control measures.
Etiological hypothesis was developed through descriptive epidemiological methods. Hypotheses were tested by analyzing epidemiological methods by comparing the differences in the incidence of different exposure types. Nucleic acid detection and bacterial isolation and culture in the BSL-2 laboratories. SPSS 21 was used to conduct statistical analysis.
A total of 126 family, workshop, shop environment samples and meat samples were collected, and 6 samples were collected from skin lesions of suspected cutaneous anthrax cases. 41 samples were positive by rPCR and 8 strains of Bacillus anthracis were cultivated. Participated in slaughtering, cutting beef of sick cattles was significantly associated with cutaneous anthrax (RR 3.75, 95% CI 1.08-13.07), this behavior is extremely dangerous.
Comprehensive analysis of laboratory results and epidemiological survey results and environmental assessments, we judge this epidemic to be an outbreak of cutaneous anthrax, associated with slaughtering and other processes from infected cattle imported from other province.
为了验证炭疽疫情的存在，确定其范围，掌握其流行病学特征，查明疫情原因并提出防控措施建议。
采用描述性流行病学方法提出病因假设，通过分析不同暴露类型发病差异来验证病因假设。在生物安全二级实验室进行核酸检测和细菌分离培养。采用 SPSS 21 软件进行统计学分析。
共采集 126 份家庭、车间、店铺环境样本和肉类样本，采集 6 份疑似皮肤炭疽病例皮肤损伤处样本。rPCR 检测结果阳性 41 份，培养出 8 株炭疽杆菌。参与宰杀、切割病牛牛肉与皮肤炭疽显著相关（RR3.75，95%CI1.08-13.07），这种行为极具危险性。
综合实验室检测结果、流行病学调查结果和环境评估结果，我们判断此次疫情为一起由外省输入感染牛引起的皮肤炭疽暴发疫情。
