Shane S M, Speedie L J, Rao L, Niedermeyer E, McPherson R
Anesth Prog. 1987 Nov-Dec;34(6):211-4.
A conscious sedation regimen consisting of alphaprodine, hydroxyzine, and methohexital together with intensive behavior modification was evaluated in an open pilot study for patients undergoing minor gynecologic surgery. This combination was found to result in hemodynamic stability, satisfactory patient compliance, and patient and surgeon acceptance. Patients were unable to recognize words taught to them just after drugs were administered.Electroencephalogram (EEG) changes seen in general anesthesia or deep sedation were not found in the EEG records of a subset of patients. These findings suggest that conscious sedation can provide adequate relief of pain and anxiety for minor gynecologic procedures when local anesthesia can achieve only partial pain relief.
在一项针对接受小型妇科手术患者的开放性初步研究中,评估了由阿法罗定、羟嗪和甲己炔巴比妥组成的清醒镇静方案以及强化行为矫正。结果发现,这种组合可实现血流动力学稳定、患者依从性良好,且患者和外科医生均表示接受。给药后,患者无法识别刚教给他们的单词。在部分患者的脑电图(EEG)记录中未发现全身麻醉或深度镇静时出现的EEG变化。这些发现表明,当局部麻醉只能部分缓解疼痛时,清醒镇静可为小型妇科手术提供足够的疼痛和焦虑缓解。