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[血细胞分离术在治疗高血微丝蚴水平罗阿丝虫病中的价值。7例结果]

[Value of cytapheresis in the treatment of loaiasis with high blood microfilaria levels. Results in 7 cases].

作者信息

Chandenier J, Pillier-Loriette C, Datry A, Rosenheim M, Danis M, Félix H, Nozais J P, Gentilini M

机构信息

Laboratoire de Parasitologie-Mycologie, Centre Hospitalier, Amiens.

出版信息

Bull Soc Pathol Exot Filiales. 1987;80(4):624-33.

PMID:3481565
Abstract

Seven patients infected with the filarial worm Loa loa received a treatment by cytapheresis in an attempt to lower the microfilaraemia. Microfilarial levels of between 6,000 and 38,500 ml, before extraction, were reduced, according to the case, by between 47 and 97% (mean 76%). The diethylcarbamazine chemotherapy which followed in 6 of 7 patients showed no sign of any of the serious side-effects which often occur in these type of cases. Due to its practicality and the fact that it is well tolerated, both clinically and biologically, cytapheresis would seem to represent the best method for initially treating loaiasis with high microfilaremia.

摘要

七名感染罗阿丝虫的患者接受了血细胞分离术治疗,以降低微丝蚴血症。根据病例,提取前微丝蚴水平在每毫升6000至38500条之间,降低了47%至97%(平均76%)。7名患者中有6名随后接受了乙胺嗪化疗,未出现这类病例中常出现的任何严重副作用迹象。由于其实用性以及在临床和生物学上耐受性良好,血细胞分离术似乎是初始治疗高微丝蚴血症罗阿丝虫病的最佳方法。

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