在罗阿丝虫病管理中，采用血液成分单采法提取微丝蚴的效用。
Usefulness of apheresis to extract microfilarias in management of loiasis.
作者信息
Muylle L, Taelman H, Moldenhauer R, Van Brabant R, Peetermans M E
出版信息
Br Med J (Clin Res Ed). 1983 Aug 20;287(6391):519-20. doi: 10.1136/bmj.287.6391.519.
Abstract
Two patients with loiasis in whom treatment with diethylcarbamazine had to be interrupted because of serious side effects underwent apheresis to extract microfilarias from the blood. After three apheresis sessions the number of microfilarias in the blood had dropped from 8980 to 3412/ml in one patient and from 2950 to 1840/ml in the other. Between 40 and 45 X 10(6) microfilarias were removed from each of the patients. After reduction of the parasitaemia the two patients were given diethylcarbamazine; no appreciable side effects occurred, and the patients were cured.
摘要
两名罗阿丝虫病患者因严重副作用而不得不中断乙胺嗪治疗，他们接受了血液成分单采术以从血液中提取微丝蚴。经过三次血液成分单采术后，一名患者血液中的微丝蚴数量从8980/ml降至3412/ml，另一名患者从2950/ml降至1840/ml。每名患者每次清除40至45×10⁶条微丝蚴。在寄生虫血症减轻后，这两名患者接受了乙胺嗪治疗；未出现明显副作用，患者被治愈。
相似文献
1
Usefulness of apheresis to extract microfilarias in management of loiasis.在罗阿丝虫病管理中，采用血液成分单采法提取微丝蚴的效用。
Br Med J (Clin Res Ed). 1983 Aug 20;287(6391):519-20. doi: 10.1136/bmj.287.6391.519.
2
Usefulness of apheresis to extract microfilarias in the management of loiasis.在罗阿丝虫病管理中采用血液成分单采术提取微丝蚴的效用。
Br Med J (Clin Res Ed). 1983 Oct 22;287(6400):1223. doi: 10.1136/bmj.287.6400.1223-a.
3
[Value of cytapheresis in the treatment of loaiasis with high blood microfilaria levels. Results in 7 cases].[血细胞分离术在治疗高血微丝蚴水平罗阿丝虫病中的价值。7例结果]
Bull Soc Pathol Exot Filiales. 1987;80(4):624-33.
4
[Value of filariopheresis in the treatment of Loa loa filariasis].[丝虫清除术在罗阿丝虫病治疗中的价值]
Pathol Biol (Paris). 1993 Apr;41(4):410-4.
5
Loa loa: the use of a blood cell separator to reduce microfilaraemia before specific chemotherapy.罗阿丝虫病：在进行特异性化疗前使用血细胞分离机降低微丝蚴血症。
J Infect. 1984 Sep;9(2):161-6. doi: 10.1016/s0163-4453(84)91195-2.
6
[Secondary effects of the treatment of hypermicrofilaremic loiasis using ivermectin].[使用伊维菌素治疗高微丝蚴血症盘尾丝虫病的继发效应]
Bull Soc Pathol Exot. 1995;88(3):105-12.
7
Apheresis in the management of loiasis with high microfilariaemia and renal disease.采用血液成分单采术治疗高微丝蚴血症和肾病的罗阿丝虫病
Br Med J (Clin Res Ed). 1986 Jan 4;292(6512):24. doi: 10.1136/bmj.292.6512.24.
8
Presence of Loa loa microfilariae in ascitic fluid.腹水液中出现罗阿丝虫微丝蚴。
J Infect Dis. 1989 Sep;160(3):559-60. doi: 10.1093/infdis/160.3.559a.
9
Destruction of microfilariae of Loa loa in the liver in loiasis treated with banocide (hetrazan).用海群生（乙胺嗪）治疗罗阿丝虫病时，肝脏中罗阿罗阿微丝蚴的破坏情况。
Trans R Soc Trop Med Hyg. 1951 Feb;44(4):470-80. doi: 10.1016/s0035-9203(51)80025-7.
10
Therapeutic apheresis using a mononuclear cell program to lower the microfilaria burden of a 23-year-old African woman with loiasis.采用单核细胞程序进行治疗性血液成分单采，以降低一名23岁患有罗阿丝虫病的非洲女性的微丝蚴负荷。
J Clin Apher. 2017 Jun;32(3):200-202. doi: 10.1002/jca.21479. Epub 2016 Jun 15.
引用本文的文献
1
Loa loa in the Vitreous Cavity of the Eye: A Case Report and State of Art.眼玻璃体内的罗阿丝虫病：一例报告及最新进展
Am J Trop Med Hyg. 2022 Aug 1;107(3):504-16. doi: 10.4269/ajtmh.22-0274.
2
An Adult Worm in the Upper Eyelid: An Atypical Presentation of Loiasis in the United States.上睑中的成虫：在美国罗阿丝虫病的一种非典型表现
Case Rep Ophthalmol Med. 2021 Apr 16;2021:6630875. doi: 10.1155/2021/6630875. eCollection 2021.
3
A Randomized, Placebo-controlled, Double-blind Pilot Study of Single-dose Humanized Anti-IL5 Antibody (Reslizumab) for the Reduction of Eosinophilia Following Diethylcarbamazine Treatment of Loa loa Infection.一项随机、安慰剂对照、双盲的初步研究，评估单次给予人源化抗 IL-5 抗体（瑞利珠单抗）对依氟鸟氨酸治疗罗阿丝虫感染后嗜酸性粒细胞增多的影响。
Clin Infect Dis. 2021 Oct 5;73(7):e1624-e1631. doi: 10.1093/cid/ciaa1365.
4
Nonsurgical management of photoaversive ocular and systemic loiasis in Michigan.密歇根州光过敏性眼部和全身性罗阿丝虫病的非手术治疗
GMS Ophthalmol Cases. 2020 Apr 15;10:Doc22. doi: 10.3205/oc000149. eCollection 2020.
5
Infection-associated Immune Perturbations Resolve 1 Year Following Treatment for Loa loa.感染相关的免疫紊乱在治疗罗阿罗阿后 1 年得到解决。
Clin Infect Dis. 2021 Mar 1;72(5):789-796. doi: 10.1093/cid/ciaa137.
6
African eye worm.非洲眼虫
J Glob Infect Dis. 2012 Apr;4(2):135-6. doi: 10.4103/0974-777X.96782.
7
Apheresis in the management of loiasis with high microfilariaemia and renal disease.采用血液成分单采术治疗高微丝蚴血症和肾病的罗阿丝虫病
Br Med J (Clin Res Ed). 1986 Jan 4;292(6512):24. doi: 10.1136/bmj.292.6512.24.
本文引用的文献
1
Encephalitis in loa-loa filariasis.罗阿丝虫病中的脑炎
J Neurol Neurosurg Psychiatry. 1955 May;18(2):103-19. doi: 10.1136/jnnp.18.2.103.
2
Ascending paralysis associated with diethylcarbamazine treatment of M. loa loa infection.
Trop Doct. 1982 Jan;12(1):16-9. doi: 10.1177/004947558201200107.
3
[Treatment of filariases in a hospital setting. Complications - results].[医院环境中丝虫病的治疗。并发症 - 结果]
Ann Soc Belg Med Trop. 1981 Jun;61(2):319-26.
4
Removal of microfilariae from unanaesthetized dogs by continuous flow centrifugation.通过连续流动离心法从未麻醉犬体内去除微丝蚴。
Trans R Soc Trop Med Hyg. 1969;63(2):259-62. doi: 10.1016/0035-9203(69)90156-4.
5
[Loaiasis with high microfilaremia. Attempted extracorporal purification after exsanguination-transfusion].[高微丝蚴血症的罗阿丝虫病。放血输血后尝试进行体外净化]
Bull Soc Pathol Exot Filiales. 1969 Sep-Oct;62(5):900-7.
6
[Current problems of loaiasis].[罗阿丝虫病的当前问题]
Bull World Health Organ. 1978;56(2):155-67.
Zotero 插件