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口服掺有他达拉非的蜂蜜后发生的中心性浆液性脉络膜视网膜病变:一例报告

Central Serous Chorioretinopathy Following Oral Use of Adulterated Honey Mixed with Tadalafil: A Case Report.

作者信息

Asharari Khalid S, Alali Naif M, Magliyah Moustafa S, Al-Dhibi Hassan A, Almarek Faisal A, AlBalawi Hani B

机构信息

Department of Ophthalmology, Prince Mohammed Medical City, Aljouf, Saudi Arabia.

Ophthalmology Division, Department of Surgery, Faculty of Medicine, University of Tabuk, Tabuk, Saudi Arabia.

出版信息

Int Med Case Rep J. 2021 Nov 15;14:773-776. doi: 10.2147/IMCRJ.S341722. eCollection 2021.

Abstract

BACKGROUND

Central serous chorioretinopathy (CSCR) is an idiopathic condition characterized by serous retinal detachment and/or retinal pigment epithelial (RPE) detachment, the condition associated with a fluid leak through the RPE into subretinal space. This article reports on an unusual case of CSCR following taking adulterated honey mixed with tadalafil powder.

CASE PRESENTATION

A 38-year-old male, not known to have any medical illnesses, came to our ophthalmology clinic complaining of sudden onset of blurred central vision in the left eye for five days after taking an adulterated honey which was claimed to improve sexual performance. On taking a history, the patient denied taking any medications or past eye trauma or surgery. On detailed ophthalmologic examination, the best-corrected visual acuity (BCVA) was 20/20 in the right eye and 20/80 in the left eye. Dilated fundus examination of the right eye showed a flat retina, normal macular reflex, healthy optic nerve head and the left eye showed blunt foveal reflex with neurosensory retinal detachment at the macula and subretinal fluid. Optical coherence tomography (OCT) of the left eye showed marked macular thickening, leading to the impression of central serous chorioretinopathy (CSCR). Four weeks after stopping the adulterated honey, BCVA improved to 20/20 in the left eye, with complete resolution of subretinal fluids.

CONCLUSION

Our case adds to recently reported cases of a link between tadalafil and CSCR.

摘要

背景

中心性浆液性脉络膜视网膜病变(CSCR)是一种特发性疾病,其特征为浆液性视网膜脱离和/或视网膜色素上皮(RPE)脱离,该疾病与液体通过RPE渗漏至视网膜下间隙有关。本文报道了一例服用掺有他达拉非粉末的蜂蜜后发生的罕见CSCR病例。

病例介绍

一名38岁男性,既往无任何疾病史,因服用声称可改善性功能的掺假蜂蜜五天后突然出现左眼中心视力模糊而前来我院眼科就诊。在询问病史时,患者否认服用任何药物或既往有眼部外伤或手术史。详细眼科检查显示,右眼最佳矫正视力(BCVA)为20/20,左眼为20/80。右眼散瞳眼底检查显示视网膜平坦,黄斑反射正常,视神经乳头健康,左眼黄斑反射迟钝,黄斑区有神经感觉性视网膜脱离及视网膜下液。左眼光学相干断层扫描(OCT)显示黄斑明显增厚,提示中心性浆液性脉络膜视网膜病变(CSCR)。停用掺假蜂蜜四周后,左眼BCVA提高至20/20,视网膜下液完全消退。

结论

我们的病例补充了最近报道的他达拉非与CSCR之间存在关联的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c20/8604643/2c44b9f4a0b0/IMCRJ-14-773-g0001.jpg

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