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一名免疫抑制患者的胃镧沉着症（镧沉积），该患者七年前停用了碳酸镧。

Gastric lanthanosis (lanthanum deposition) in an immunosuppressed patient that discontinued lanthanum carbonate seven years ago.

作者信息

Ullmann Joana M, Erbersdobler Andreas

机构信息

Institute of Pathology University Medicine Rostock Strempelstr. 14 Rostock 18057 Germany.

出版信息

Clin Case Rep. 2021 Nov 16;9(11):e05075. doi: 10.1002/ccr3.5075. eCollection 2021 Nov.

DOI:10.1002/ccr3.5075
PMID:34815874
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8594568/
Abstract

A 72-year-old female patient used the oral phosphate binder lanthanum carbonate for 6 years, before discontinuing it after receiving a pancreas and kidney transplant. Now, 7 years after discontinuation, the patient developed bilious emesis. An upper gastrointestinal endoscopy showed an unspecific gastritis. Biopsies showed subepithelial crystalline deposits consistent with gastric lanthanosis.

摘要

一名72岁女性患者口服碳酸镧磷酸盐结合剂6年，在接受胰腺和肾脏移植后停药。现在，停药7年后，该患者出现胆汁性呕吐。上消化道内镜检查显示为非特异性胃炎。活检显示上皮下结晶沉积物，符合胃镧中毒表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/766b/8594568/825151e2ba12/CCR3-9-e05075-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/766b/8594568/5eda5982c213/CCR3-9-e05075-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/766b/8594568/825151e2ba12/CCR3-9-e05075-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/766b/8594568/5eda5982c213/CCR3-9-e05075-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/766b/8594568/825151e2ba12/CCR3-9-e05075-g001.jpg

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本文引用的文献

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Investigation of the clinical significance and pathological features of lanthanum deposition in the gastric mucosa.研究胃黏膜中镧沉积的临床意义和病理特征。
BMC Gastroenterol. 2020 Nov 23;20(1):396. doi: 10.1186/s12876-020-01545-z.
2
Deposition patterns of iatrogenic lanthanum and gadolinium in the human body depend on delivered chemical binding forms.医源性镧和钆在人体内的沉积模式取决于所输送的化学结合形式。
J Trace Elem Med Biol. 2021 Jan;63:126665. doi: 10.1016/j.jtemb.2020.126665. Epub 2020 Oct 24.
3
Gastropathy associated with lanthanum phosphate deposition that was endoscopically tracked for 3 years. A case report.
胃疾病与磷酸镧沉积相关，该沉积通过内镜追踪 3 年。病例报告。
BMC Gastroenterol. 2020 Aug 31;20(1):292. doi: 10.1186/s12876-020-01424-7.
4
Review of the diagnosis of gastrointestinal lanthanum deposition.胃肠道镧沉积的诊断评价。
World J Gastroenterol. 2020 Apr 7;26(13):1439-1449. doi: 10.3748/wjg.v26.i13.1439.
5
Lanthanum Deposition in the Gastroduodenal Mucosa of Dialysis Patients.镧在透析患者胃十二指肠黏膜中的沉积
J UOEH. 2019;41(4):387-395. doi: 10.7888/juoeh.41.387.
6
Lanthanum-Induced Radiopaque Intestinal Precipitates: A Potential Cause of Intestinal Foreign Bodies.镧诱导的不透射线肠道沉淀物：肠道异物的一个潜在原因。
Case Rep Nephrol. 2019 Sep 2;2019:1298674. doi: 10.1155/2019/1298674. eCollection 2019.
7
Case of early-stage gastric cancer identified in the gastric mucosa with lanthanum phosphate deposition.在胃黏膜中发现伴有磷酸镧沉积的早期胃癌病例。
Endosc Int Open. 2019 Jul;7(7):E893-E895. doi: 10.1055/a-0918-5804. Epub 2019 Jul 3.
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Intern Med. 2019 Aug 15;58(16):2283-2289. doi: 10.2169/internalmedicine.2398-18. Epub 2019 May 22.
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