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仅通过源头控制成功治疗快速生长分枝杆菌感染:病例系列

Successful treatment of rapid growing mycobacterial infections with source control alone: Case series.

作者信息

Dumic Igor, Lutwick Larry

机构信息

Mayo Clinic College of Medicine and Science, Rochester, MN, USA.

Division of Hospital Medicine, Mayo Clinic Health System, Eau Claire, WI, USA.

出版信息

IDCases. 2021 Nov 6;26:e01332. doi: 10.1016/j.idcr.2021.e01332. eCollection 2021.

Abstract

Rapid growing mycobacteria have been increasingly recognized as pathogens, both in immunocompromised and immunocompetent population, and their incidence has increased over the last decade significantly. Pulmonary infections are the most common, however, any organ can be affected. The treatment of these infections is costly, prolonged, and often antimicrobial resistance poses a significant challenge to a successful outcome. The source control together with antimicrobials is the cornerstone of treatment. We report a case series of 3 patients with extrapulmonary rapid growing mycobacterial infections in whom the successful treatment was achieved with source control alone.

摘要

快速生长分枝杆菌已越来越被认为是病原体,在免疫功能低下和免疫功能正常人群中均如此,且在过去十年中其发病率显著增加。肺部感染最为常见,然而,任何器官都可能受累。这些感染的治疗成本高、疗程长,而且抗菌药物耐药性常常给治疗成功带来重大挑战。源头控制与抗菌药物联用是治疗的基石。我们报告了一组3例肺外快速生长分枝杆菌感染患者的病例系列,这些患者仅通过源头控制就实现了成功治疗。

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