Department of Rehabilitation Medicine, 37976Keimyung University School of Medicine, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, Republic of Korea.
Department of Neurology, 37976Keimyung University School of Medicine, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, Republic of Korea.
J Int Med Res. 2021 Nov;49(11):3000605211056783. doi: 10.1177/03000605211056783.
The ongoing global administration of vaccines for coronavirus disease 2019 (COVID-19) means that increasing numbers of patients are likely to present with post-vaccination complications. We describe the first reported case of neuralgic amyotrophy (NA) involving the lumbosacral plexus occurring after AstraZeneca COVID-19 vaccination. The patient presented with acute-onset leg paralysis following administration of the vaccine. Based on the clinical, electrodiagnostic, and radiologic findings, the patient was diagnosed with post-vaccination NA. We speculate that the COVID-19 vaccine elicited an immune-mediated inflammatory response to the injected antigen due to inflammatory immunity in a patient with predisposed susceptibility to NA.
正在进行的 2019 年冠状病毒病（COVID-19）疫苗全球接种意味着越来越多的患者可能出现疫苗接种后并发症。我们描述了首例阿斯特捷利康 COVID-19 疫苗接种后累及腰骶丛的神经痛性肌萎缩（NA）病例。患者在接种疫苗后出现急性下肢瘫痪。根据临床、电诊断和影像学检查结果，该患者被诊断为疫苗接种后 NA。我们推测 COVID-19 疫苗引起了注射抗原的免疫介导的炎症反应，这是由于易感 NA 的患者存在炎症免疫。
