School of Medicine, Eulji University, Jung-gu, Daejeon, South Korea (Dr Kim); Department of Healthcare Management, Graduate School of Public Health, Yonsei University, Seodaemun-gu, Seoul, South Korea (Dr Jang).
J Occup Environ Med. 2022 Mar 1;64(3):190-196. doi: 10.1097/JOM.0000000000002445.
This study aimed to investigate the relationship between long working hours and chronic kidney disease (CKD) according to diabetic status.
Twelve thousand seven hundred three full-time employees without diabetes and 2136 with diabetes were included in this study. Participants were grouped according to working hours: ≤40, 41 to 52, and >52 h/week. Multiple logistic regression was used to evaluate the association between working hours and CKD prevalence.
Participants with diabetes who worked 41 to 52 h/week showed 1.85 times higher odds of CKD (95% CI 1.15-2.96; P = 0.0112) compared with those who worked ≤40 h/week after adjusting for covariates. An interaction between diabetes and long working hours was observed (P for interaction = 0.0212) in the model.
Long working hours are associated with CKD in participants with diabetes. An interaction between long working hours and diabetes leading to CKD development may exist.
本研究旨在根据糖尿病患病情况，探讨长工时与慢性肾脏病（CKD）之间的关系。
本研究共纳入 12703 名无糖尿病的全职员工和 2136 名糖尿病患者。参与者根据工作时间分为≤40、41-52 和>52 小时/周三组。采用多因素 logistic 回归分析评估工作时间与 CKD 患病率之间的关系。
校正混杂因素后，每周工作 41-52 小时的糖尿病患者发生 CKD 的几率是每周工作≤40 小时的 1.85 倍（95%CI 1.15-2.96；P=0.0112）。模型中观察到糖尿病和长工时之间存在交互作用（P 交互=0.0212）。
长工时与糖尿病患者的 CKD 相关。长工时和糖尿病之间可能存在相互作用，导致 CKD 的发生。
