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腹腔镜胃底折叠术:一种用于治疗胃旁路术后难治性胆汁反流的新方法。

Laparoscopic Fundoplication Using the Excluded Stomach as a Novel Management Option for Refractory Bile Reflux Following One Anastomosis Gastric Bypass (OAGB).

机构信息

St John of God Hospital, Corner Robertson Drive & Bussell Highway Bunbury, PO Box 5007, Bunbury, WA, 6231, Australia.

出版信息

Obes Surg. 2022 Feb;32(2):561-566. doi: 10.1007/s11695-021-05804-0. Epub 2021 Nov 24.

DOI:10.1007/s11695-021-05804-0
PMID:34817792
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8795036/
Abstract

BACKGROUND

One anastomosis gastric bypass (OAGB) is now a mainstream bariatric procedure. Refractory gastroesophageal reflux is a significant complication following OAGB, and conversion to Roux-en-Y has long been the treatment of choice for this issue. Strengthening the lower esophageal sphincter by Nissen fundoplication (NF) has been reported as an effective anti-reflux surgery. Here we report the short-term outcomes of a modified NF procedure using the excluded stomach (excluded stomach fundoplication-ESF) to treat refractory bile reflux in post-OAGB patients.

METHODS

Thirteen post-OAGB patients underwent ESF for refractory bile reflux during the study, as detailed in the surgical technique. This paper reports the 12 patients whose follow-up data are available.

RESULTS

Following ESF, the GERD-HRQL heartburn score improved from 22.7 ± 3.9 to 1.8 ± 3.5 (p < 0.05). The mean aggregate GERD-HRQL score improved from 27.9 ± 5.3 to 5.7 ± 5.9 (p < 0.05). The GERD-HRQL global satisfaction score showed that 100% of patients were satisfied with the improvement of symptoms. The mean VISICK score improved from 3.8 ± 0.39 to 1.2 ± 0.39 (p < 0.05). One patient was returned to the operating theatre to have the wrap loosened due to dysphagia. Eleven patients did not require PPIs after surgery.

CONCLUSIONS

ESF significantly improved the VISICK score and GERD-HRQL of post-OAGB patients with refractory bile reflux in the short term. The current study is being continued to increase the sample size and the follow-up period.

摘要

背景

单吻合胃旁路术(OAGB)现已成为主流的减重手术。术后难治性胃食管反流是 OAGB 的一个重要并发症,长期以来,胃转流术(Roux-en-Y)一直是治疗该问题的首选方法。通过 Nissen 胃底折叠术(NF)加强下食管括约肌已被报道为一种有效的抗反流手术。在此,我们报告了一种改良的 NF 手术,使用被排除的胃(排除胃底折叠术 - ESF)来治疗 OAGB 后难治性胆汁反流的短期结果。

方法

在研究期间,13 例 OAGB 后患者因难治性胆汁反流而行 ESF,详见手术技术。本文报告了 12 例可获得随访数据的患者。

结果

行 ESF 后,GERD-HRQL 烧心评分从 22.7±3.9 改善至 1.8±3.5(p<0.05)。平均综合 GERD-HRQL 评分从 27.9±5.3 改善至 5.7±5.9(p<0.05)。GERD-HRQL 总体满意度评分显示,100%的患者对症状改善感到满意。平均 VISICK 评分从 3.8±0.39 改善至 1.2±0.39(p<0.05)。1 例患者因吞咽困难返回手术室松解包裹。11 例患者术后无需质子泵抑制剂。

结论

ESF 可显著改善 OAGB 后难治性胆汁反流患者的 VISICK 评分和 GERD-HRQL,短期疗效显著。目前,该研究正在继续增加样本量和随访时间。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ac3/8795036/5e7e80979cc1/11695_2021_5804_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ac3/8795036/59c971eb30f6/11695_2021_5804_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ac3/8795036/5e7e80979cc1/11695_2021_5804_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ac3/8795036/59c971eb30f6/11695_2021_5804_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ac3/8795036/5e7e80979cc1/11695_2021_5804_Fig2_HTML.jpg

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