Hu H Y, Chen Y H, Zhou Y, Zhang Z, Lu J, Liu X Y, Chen L P, Fu G F
Department of AIDS/STD Prevention and Control, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2021 Nov 10;42(11):1989-1993. doi: 10.3760/cma.j.cn112338-20210601-00441.
To understand the incidence of HIV infections and associated factors among men who have sex with men (MSM) in Jiangsu province. Based on national AIDS sentinel surveillance in 2019, MSM from 13 cities in Jiangsu were recruited for questionnaire interview and laboratory testing during April to July, 2019. Seropositive samples were tested with Limiting-antigen avidity enzyme immunoassay to detect recent HIV infections. The incidence of HIV infection in MSM were calculated according to the formula and parameters from China CDC. Multivariable logistic regression analysis was used to identify factors associated with recent infection of HIV. A total of 4 469 MSM were subjects and the incidence of HIV infection were 4.5% (95%: 3.4%-5.5%).Multivariate logistic regression analysis results showed that compared with these aged ≥40 years, recruitment ways from MSM venues, awareness of AIDS knowledge, non-unprotected anal sex in the past 6 months and non-syphilis infection, those who aged 18-24 years (a=2.083,95%:1.087-3.990), recruitment ways from VCT clinics (a=2.125,95%:1.175-3.843), unawareness of AIDS knowledge (a=2.456,95%:1.109-5.437), unprotected anal sex in the past 6 months (a=3.553,95%:2.143-5.889) and syphilis infection (a=2.414,95%:1.033-5.462) were higher risk of HIV infection. The new infection rates of HIV were high in MSM in Jiangsu province. Health education, condom use and HIV/syphilis screening promotions should therefore be top priority in the prevention and control of HIV infection in MSM.
了解江苏省男男性行为者（MSM）中HIV感染的发生率及相关因素。基于2019年全国艾滋病哨点监测，招募江苏省13个城市的MSM于2019年4月至7月进行问卷调查和实验室检测。血清学阳性样本采用限量抗原亲和力酶免疫测定法检测近期HIV感染情况。根据中国疾病预防控制中心的公式和参数计算MSM中HIV感染的发生率。采用多变量logistic回归分析确定与近期HIV感染相关的因素。共有4469名MSM作为研究对象，HIV感染发生率为4.5%（95%：3.4%-5.5%）。多变量logistic回归分析结果显示，与年龄≥40岁、从MSM场所招募、知晓艾滋病知识、过去6个月无肛交不安全性行为以及无梅毒感染的人群相比，年龄在18-24岁（a=2.083，95%：1.087-3.990）、从自愿咨询检测（VCT）门诊招募（a=2.125，95%：1.175-3.843）、不知晓艾滋病知识（a=2.456，95%：1.109-5.437）、过去6个月有肛交不安全性行为（a=3.553，95%：2.143-5.889）以及有梅毒感染（a=2.414，95%：1.033-5.462）的人群感染HIV的风险更高。江苏省MSM中HIV新发感染率较高。因此，健康教育、推广使用避孕套以及开展HIV/梅毒筛查应成为MSM人群HIV感染防控工作的重中之重。
