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前路肌间沟阻滞与切口浸润在机器人辅助胸腔镜手术中的比较:一项随机对照的初步研究。

Serratus Anterior Plane Block Versus Intercostal Block with Incision Infiltration in Robotic-Assisted Thoracoscopic Surgery: A Randomized Controlled Pilot Trial.

机构信息

Mount Sinai West - Morningside Hospitals, Department of Anesthesiology, Perioperative and Pain Medicine, New York, USA.

Icahn School of Medicine at Mount Sinai, Department of Anesthesiology, Perioperative and Pain Medicine, New York, USA.

出版信息

J Cardiothorac Vasc Anesth. 2022 Aug;36(8 Pt A):2287-2294. doi: 10.1053/j.jvca.2021.10.022. Epub 2021 Oct 27.

Abstract

OBJECTIVES

Patients undergoing robotic video-assisted thoracoscopic surgery (rVATS) report significant postoperative pain. Both the serratus anterior plane block (SAPB) and the surgical intercostal block (IB) (performed by a surgeon from within the thorax), along with incision infiltration (II), are distinct modalities that target the lateral cutaneous branches of intercostal nerves and are acceptable analgesic modalities in an enhanced recovery after rVATS surgery.

DESIGN

Prospective, double-blinded, randomized, controlled pilot trial with 65 patients to assess the difference in analgesia quality between the SAPB and IB+II in rVATS.

SETTING

Major academic teaching hospital.

PARTICIPANTS

The inclusion criteria included ASA physical status I-IV, ages 18-to-75 undergoing an elective, unilateral rVATS procedure.

INTERVENTIONS

Patients were randomized to receive either an ultrasound-guided SAPB at the end of their surgery, using a 20-mL mixture consisting of 10 mL of liposomal bupivacaine (133 mg) and 10 mL 0.25% bupivacaine, or IB+II, using a 20-mL mixture consisting of 10 mL of liposomal bupivacaine (133 mg) and 10 mL 0.5% bupivacaine prior to skin closure by the surgeon.

RESULTS

The primary outcome was the amount of postoperative opioid consumption in morphine milliequivalents [MME] during the first 24 hours after surgery. Secondary outcomes were time to first analgesic request, VAS scores at zero, two, six, 18, or 24 hours at rest, and PACU, ICU, or hospital lengths of stay (LOS). There were no differences in any outcomes between the groups.

CONCLUSIONS

Both SAPB and IB+II are comparable analgesic modalities for rVATS procedures.

摘要

目的

接受机器人辅助电视胸腔镜手术(rVATS)的患者报告有明显的术后疼痛。前锯肌平面阻滞(SAPB)和外科肋间阻滞(IB)(由胸腔内的外科医生进行)以及切口浸润(II)都是针对肋间神经皮支的不同方式,是 rVATS 手术后加速康复的可接受的镇痛方式。

设计

前瞻性、双盲、随机、对照的初步试验,纳入 65 例患者,评估 rVATS 中 SAPB 和 IB+II 对镇痛质量的差异。

设置

主要学术教学医院。

参与者

纳入标准包括 ASA 身体状况 I-IV 级,年龄 18-75 岁,接受择期单侧 rVATS 手术。

干预

患者随机接受手术结束时的超声引导 SAPB,使用包含 10 mL 脂质体布比卡因(133 mg)和 10 mL 0.25%布比卡因的 20-mL 混合物,或在外科医生闭合皮肤前接受 IB+II,使用包含 10 mL 脂质体布比卡因(133 mg)和 10 mL 0.5%布比卡因的 20-mL 混合物。

结果

主要结果是术后 24 小时内吗啡消耗量的术后阿片类药物消耗量(以吗啡毫当量[MME]计)。次要结果是首次镇痛需求的时间、零、两、六、18 或 24 小时时的 VAS 评分、PACU、ICU 或住院时间(LOS)。两组在任何结果上均无差异。

结论

SAPB 和 IB+II 都是 rVATS 手术的等效镇痛方式。

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