Hiramoto Brent, Liu Yao, Dara Lily, Zhou Kali
Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA.
Division of Gastrointestinal and Liver Diseases, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles CA.
ACG Case Rep J. 2021 Nov 22;8(11):e00702. doi: 10.14309/crj.0000000000000702. eCollection 2021 Nov.
Hepatitis A (HAV) has emerged in outbreaks across the United States particularly in at-risk populations such as men who have sex with men, as well as patients with a history of drug use, homelessness, and incarceration. Immunization among these high-risk populations remains underused. In this study, we describe a case of acute HAV and hepatitis B (HBV) coinfection in an MSM patient occurring in the period of these outbreaks. Clinical resolution of acute HAV and HBV coinfection was attained by 5 months from the time of initial hospitalization without viral hepatitis treatment. This case highlights the need for increased awareness of at-risk populations for HAV and HBV infection in promoting guideline-based vaccination efforts.
甲型肝炎(HAV)在美国各地的疫情中出现,特别是在男男性行为者、有吸毒史、无家可归和曾被监禁等高危人群中。这些高危人群的免疫接种使用率仍然较低。在本研究中,我们描述了在这些疫情期间发生的一例男男性行为者急性HAV和乙型肝炎(HBV)合并感染病例。从初次住院起5个月内,未经病毒性肝炎治疗,急性HAV和HBV合并感染获得临床缓解。该病例凸显了在促进基于指南的疫苗接种工作中,提高对HAV和HBV感染高危人群认识的必要性。