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改变妇产科的红细胞输血实践:医院范围教育的前后研究。

Changing red blood cell transfusion practice in obstetrics and gynaecology: A before and after study of hospital-wide education.

机构信息

University of Saskatchewan, College of Medicine, Regina, Canada.

Department of Research, Saskatchewan Health Authority, Regina, Canada.

出版信息

Transfus Med. 2022 Feb;32(1):38-44. doi: 10.1111/tme.12839. Epub 2021 Nov 24.

Abstract

OBJECTIVES

To assess transfusion practices at a Canadian tertiary care center before and after a hospital-wide blood management educational campaign based on the Choosing Wisely toolkit.

BACKGROUND

Red blood cell (RBC) transfusions are an essential intervention in obstetrics and gynaec ology (O&G). However, with limited guidelines outlining the appropriate use of RBC transfusions, clinicians routinely transfuse based on haemoglobin values and habits.

METHODS/MATERIALS: We conducted a retrospective chart review of all patients who received a RBC transfusion while admitted under an O&G provider in two 12-month periods-before and after the intervention. The campaign consisted of Grand Rounds, formal and informal teaching, and posters placed within the hospital. We judged appropriateness from a set of criteria guided by the status of ongoing bleeding, pre-transfusion haemoglobin, and the number of units ordered simultaneously.

RESULTS

Transfusion appropriateness was poor in pre- and post-intervention periods (46% vs. 51%, p = 0.59). The overall rate of RBC transfusion was reduced from 1.8% to 1.2% (83/4610 vs. 55/4618, p = 0.02) after the intervention. There was a 52% reduction in the total number of RBC units of transfused (229 vs. 111, p < 0.001), a 33% reduction in the number of patients transfused (83 vs. 55, p = 0.016), and fewer multiple-unit transfusions without reassessment (39 vs. 13, p = 0.005).

CONCLUSION

RBC transfusion appropriateness remained low after a hospital-wide educational campaign. However, there was a marked decrease in overall transfusion use, reflecting the adoption of more restrictive transfusion practices. The low rate of transfusion appropriateness represents an opportunity for further improvement.

摘要

目的

在基于明智选择工具包的全院血液管理教育活动之前和之后,评估一家加拿大三级保健中心的输血实践。

背景

红细胞(RBC)输血是妇产科的重要干预措施。然而,由于有限的指南概述了 RBC 输血的适当用途,临床医生通常根据血红蛋白值和习惯进行输血。

方法/材料:我们对在妇产科医生治疗下住院的所有接受 RBC 输血的患者进行了回顾性图表审查,分为干预前和干预后两个 12 个月的时间段。该活动包括大查房、正式和非正式教学以及在医院内张贴海报。我们根据一系列标准来判断输血的适当性,这些标准由正在进行的出血状态、输血前血红蛋白和同时订购的单位数量指导。

结果

干预前和干预后输血的适当性都很差(分别为 46%和 51%,p=0.59)。干预后,RBC 输血的总体比例从 1.8%降至 1.2%(83/4610 对 55/4618,p=0.02)。总的 RBC 单位输注量减少了 52%(229 对 111,p<0.001),输血患者减少了 33%(83 对 55,p=0.016),且没有重新评估的多次输血减少了 39 对 13(p=0.005)。

结论

在全院范围的教育活动之后,RBC 输血的适当性仍然较低。然而,整体输血使用率明显下降,反映了更严格的输血实践的采用。低输血适当性率代表了进一步改进的机会。

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