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基于石墨烯/金/碳化硅波导的表面等离子体共振传感器的数值研究。

Numerical Study of Graphene/Au/SiC Waveguide-Based Surface Plasmon Resonance Sensor.

机构信息

Department of Electrical Engineering and Physics, Wilkes University, Wilkes-Barre, PA 18766, USA.

Micro/Nanoelectronics and Energy Laboratory, School of Engineering and Computer Science, Washington State University, Vancouver, WA 98686, USA.

出版信息

Biosensors (Basel). 2021 Nov 15;11(11):455. doi: 10.3390/bios11110455.

Abstract

A new waveguide-based surface plasmon resonance (SPR) sensor was proposed and investigated by numerical simulation. The sensor consists of a graphene cover layer, a gold (Au) thin film, and a silicon carbide (SiC) waveguide layer on a silicon dioxide/silicon (SiO/Si) substrate. The large bandgap energy of SiC allows the sensor to operate in the visible and near-infrared wavelength ranges, which effectively reduces the light absorption in water to improve the sensitivity. The sensor was characterized by comparing the shift of the resonance wavelength peak with change of the refractive index (RI), which mimics the change of analyte concentration in the sensing medium. The study showed that in the RI range of 1.331.36, the sensitivity was improved when the graphene layers were increased. With 10 graphene layers, a sensitivity of 2810 nm/RIU (refractive index unit) was achieved, corresponding to a 39.1% improvement in sensitivity compared to the Au/SiC sensor without graphene. These results demonstrate that the graphene/Au/SiC waveguide SPR sensor has a promising use in portable biosensors for chemical and biological sensing applications, such as detection of water contaminations (RI = 1.331.34), hepatitis B virus (HBV), and glucose (RI = 1.341.35), and plasma and white blood cells (RI = 1.351.36) for human health and disease diagnosis.

摘要

一种基于波导的新型表面等离子体共振(SPR)传感器通过数值模拟被提出并进行了研究。该传感器由一个石墨烯覆盖层、一个金(Au)薄膜和一个碳化硅(SiC)波导层组成,位于二氧化硅/硅(SiO/Si)衬底上。SiC 的大带隙能量允许传感器在可见和近红外波长范围内工作,这有效地减少了水中的光吸收,提高了灵敏度。该传感器的特点是通过比较共振波长峰值的位移与折射率(RI)的变化来进行特征描述,这模拟了传感介质中分析物浓度的变化。研究表明,在 RI 范围为 1.331.36 时,增加石墨烯层可以提高灵敏度。当有 10 层石墨烯时,实现了 2810nm/RIU(折射率单位)的灵敏度,与没有石墨烯的 Au/SiC 传感器相比,灵敏度提高了 39.1%。这些结果表明,石墨烯/Au/SiC 波导 SPR 传感器在用于化学和生物传感应用的便携式生物传感器中具有广阔的应用前景,例如检测水污染(RI = 1.331.34)、乙型肝炎病毒(HBV)和葡萄糖(RI = 1.341.35)以及用于人体健康和疾病诊断的等离子体和白细胞(RI = 1.351.36)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2ed/8615979/e5d85f2ba9ce/biosensors-11-00455-g001.jpg

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