The Matilda Centre for Research in Mental Health & Substance Use, The University of Sydney, Australia.
The Matilda Centre for Research in Mental Health & Substance Use, The University of Sydney, Australia.
J Am Acad Child Adolesc Psychiatry. 2022 Apr;61(4):520-532. doi: 10.1016/j.jaac.2021.10.023. Epub 2021 Nov 22.
Alcohol use is a leading cause of burden of disease among young people. Prevention strategies can be effective in the short-term; however little is known about their longer-term effectiveness. The aim of this study was to examine the sustainability of universal, selective, and combined alcohol use prevention across the critical transition period from adolescence into early adulthood.
In 2012, a total of 2190 students (mean age, 13.3 years) from 26 Australian high schools participated in a cluster randomized controlled trial and were followed up for 3 years post baseline. Schools were randomly assigned to deliver the following: (1) universal Web-based prevention for all students (Climate Schools); (2) selective prevention for high-risk students (Preventure); (3) combined universal and selective prevention (Climate Schools and Preventure [CAP]); or (4) health education as usual (control). This study extends the follow-up period to 7-years post baseline. Primary outcomes were self-reported frequency of alcohol consumption and binge drinking, alcohol-related harms, and hazardous alcohol use, at the 7-year follow-up.
At 7-year follow-up, students in all 3 intervention groups reported reduced odds of alcohol-related harms compared to the control group (odds ratios [ORs] = 0.13-0.33), and the Climate (OR = 0.04) and Preventure (OR = 0.17) groups reported lower odds of hazardous alcohol use. The Preventure group also reported lower odds of weekly alcohol use compared to the control group (OR = 0.17), and the Climate group reported lower odds of binge drinking (OR = 0.12), holding mean baseline levels constant.
This study demonstrated that both universal and selective preventive interventions delivered in schools can have long-lasting effects and reduce risky drinking and related harms into adulthood. No added benefit was observed by delivering the combined interventions.
The CAP Study: Evaluating a Comprehensive Universal and Targeted Intervention Designed to Prevent Substance Use and Related Harms in Australian Adolescents; https://www.anzctr.org.au/; ACTRN12612000026820.
饮酒是导致年轻人疾病负担的主要原因之一。预防策略在短期内可能有效;然而,对于其长期效果知之甚少。本研究旨在考察普遍性、选择性和联合的酒精使用预防措施在青少年向成年早期的关键过渡时期的可持续性。
2012 年,来自澳大利亚 26 所高中的 2190 名学生(平均年龄 13.3 岁)参与了一项整群随机对照试验,并在基线后 3 年进行了随访。学校被随机分配实施以下措施:(1)面向所有学生的基于网络的普遍性预防(气候学校);(2)对高风险学生的选择性预防(预防);(3)普遍和选择性预防相结合(气候学校和预防[CAP]);或(4)常规健康教育(对照组)。本研究将随访时间延长至基线后 7 年。主要结局指标为 7 年随访时的自我报告饮酒频率和狂饮、酒精相关危害和危险饮酒。
在 7 年随访时,与对照组相比,所有 3 个干预组的学生报告的酒精相关危害的可能性降低(比值比[OR]为 0.13-0.33),气候组(OR=0.04)和预防组(OR=0.17)报告的危险饮酒可能性也较低。与对照组相比,预防组每周饮酒的可能性也较低(OR=0.17),而气候组报告的狂饮可能性较低(OR=0.12),在保持平均基线水平不变的情况下。
本研究表明,在学校实施的普遍性和选择性预防干预措施都可以产生持久的效果,并减少成年后危险饮酒和相关危害。联合干预没有观察到额外的益处。
CAP 研究:评估旨在预防澳大利亚青少年物质使用和相关危害的综合普遍和有针对性的干预措施;https://www.anzctr.org.au/;ACTRN12612000026820。