University of South Florida, Morsani College of Medicine, 13000 Bruce B Downs Boulevard, VAR 111D, Tampa, FL 33612, USA.
University of South Florida, Morsani College of Medicine, 13000 Bruce B Downs Boulevard, VAR 111D, Tampa, FL 33612, USA; Division of Allergy and Immunology, Department of Internal Medicine, James A. Haley VA Hospital, Tampa, FL, USA.
Immunol Allergy Clin North Am. 2022 Feb;42(1):1-11. doi: 10.1016/j.iac.2021.09.001.
There are many definitions of anaphylaxis in the medical literature. The authors propose a modified definition of anaphylaxis to be used for clinical decision making that promotes the early utilization of intramuscular epinephrine. Anaphylaxis can be a result of an allergic or nonallergic mechanism. In general, allergic reactions are more severe; however, any type of anaphylaxis can result in death and improve with IM epinephrine. The World Allergy Organization's Grading Criteria for allergic systemic reactions are adapted as a guide to identify manifestations that may progress to anaphylaxis. The intent is to promote and encourage the use of IM epinephrine in the health care setting before the progression of manifestations and the onset of life-threatening respiratory or cardiovascular dysfunction generally recognized as meeting the definition of anaphylaxis.
医学文献中有许多关于过敏反应的定义。作者提出了一种改良的过敏反应定义，用于临床决策，以促进尽早使用肌肉内肾上腺素。过敏反应可能是过敏或非过敏机制的结果。一般来说，过敏反应更严重；然而，任何类型的过敏反应都可能导致死亡，并且可以通过 IM 肾上腺素改善。世界过敏组织的全身性过敏反应分级标准被用作识别可能进展为过敏反应的表现的指南。其目的是在表现进展和危及生命的呼吸或心血管功能障碍出现之前，在医疗保健环境中推广和鼓励使用 IM 肾上腺素，通常认为这符合过敏反应的定义。
