营养与结缔组织病。

Nutrition and connective tissue disease.

机构信息

Frank H. Netter MD School of Medicine, Quinnipiac University, North Haven, Connecticut, USA.

Department of Dermatology, University of Connecticut Medical Center, Farmington, Connecticut, USA.

出版信息

Clin Dermatol. 2022 Mar-Apr;40(2):166-172. doi: 10.1016/j.clindermatol.2021.10.010. Epub 2021 Oct 26.

DOI:10.1016/j.clindermatol.2021.10.010

PMID:34823904

Abstract

Despite an incomplete overall understanding, nutrition plays an important role in connective tissue disease. Assessment of patients with connective tissue disease for nutritional status and metabolic disturbances may significantly contribute to patient outcomes. Several studies have indicated the multifactorial role of macronutrients, micronutrients, and supplements in the setting of connective tissue disease. There is additional evidence regarding the roles of weight, obesity, and malnutrition. This contribution reviews a growing body of data regarding nutrition in the development and treatment of various connective tissue diseases, including systemic lupus erythematosus, dermatomyositis, and systemic sclerosis.

摘要

尽管整体认识尚不完整，但营养在结缔组织疾病中起着重要作用。评估结缔组织疾病患者的营养状况和代谢紊乱可能对患者的预后有重要贡献。多项研究表明，在结缔组织疾病中，宏量营养素、微量营养素和补充剂具有多方面的作用。还有更多证据表明体重、肥胖和营养不良的作用。本综述回顾了关于营养在各种结缔组织疾病（包括系统性红斑狼疮、皮肌炎和系统性硬化症）的发生和治疗中的作用的不断增加的数据。