Cuesta-Montero L, Belinchón I
Sección de Dermatología, Hospital General Universitario de Alicante, España.
Actas Dermosifiliogr. 2011 Sep;102(7):487-97. doi: 10.1016/j.ad.2011.03.002. Epub 2011 May 4.
Psoriasis is an autoimmune chronic inflammatory skin disease that is common in Spain. Connective tissue diseases are a heterogeneous group of conditions characterized by the abnormal function or structure of one or more of the elements that make up connective tissue. These diseases are also autoimmune in origin. In spite of the high prevalence of psoriasis in the general population, its association with a connective tissue disease such as systemic lupus erythematosus, dermatomyositis, scleroderma, or rheumatoid arthritis has only occasionally been reported. It is nevertheless important to have an understanding of such associations, given their significant clinical and therapeutic implications. The association between psoriasis and systemic lupus erythematosus is the one most often described, although the few reports available in the literature have mostly involved single cases. This review will also look at the characteristics of patients with psoriasis and dermatomyositis, mainly focusing on clinical features. The associations between psoriasis and either rheumatoid arthritis or systemic sclerosis will be examined more briefly. The review therefore aims to reflect the literature on psoriasis in association with rheumatic diseases, including coverage of etiologic, pathogenic, clinical, and therapeutic aspects. We emphasize that such cases should be managed by a multidisciplinary team in which care will usually be shared by a rheumatologist and a dermatologist.
银屑病是一种自身免疫性慢性炎症性皮肤病，在西班牙很常见。结缔组织病是一组异质性疾病，其特征是构成结缔组织的一种或多种成分的功能或结构异常。这些疾病也起源于自身免疫。尽管银屑病在普通人群中患病率很高，但它与系统性红斑狼疮、皮肌炎、硬皮病或类风湿关节炎等结缔组织病的关联仅偶尔有报道。然而，鉴于它们具有重要的临床和治疗意义，了解这种关联很重要。银屑病与系统性红斑狼疮之间的关联是最常被描述的，尽管文献中现有的少数报告大多涉及个别病例。本综述还将探讨银屑病和皮肌炎患者的特征，主要关注临床特征。银屑病与类风湿关节炎或系统性硬化症之间的关联将进行更简要的探讨。因此，本综述旨在反映关于银屑病与风湿性疾病关联的文献，包括病因、发病机制、临床和治疗方面的内容。我们强调，此类病例应由多学科团队管理，通常由风湿病学家和皮肤科医生共同提供护理。
