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英国三级皮肤癌服务中微创腹股沟淋巴结清扫术的介绍:初步经验和结果。

Introducing minimally invasive inguinal lymph node dissection in a UK tertiary skin cancer service: Initial experience & outcomes.

机构信息

Department of Plastic & Reconstructive Surgery, Colney Lane, Norwich NR4 7UY, UK.

Department of Urology, Norfolk and Norwich University Hospital, Colney Lane, Norwich NR4 7UY, UK.

出版信息

J Plast Reconstr Aesthet Surg. 2022 Feb;75(2):737-742. doi: 10.1016/j.bjps.2021.09.054. Epub 2021 Oct 22.

Abstract

AIMS

We report the first UK case series of minimally invasive inguinal lymphadenectomy (MILND) for patients with metastatic cutaneous pathology.

METHODS

This was a retrospective, single-centre, single-surgeon cohort study. Twenty-one patients who underwent MILND from May 2015 to February 2019 were included. Demographic data, disease burden, and surgical quality assurance parameters were analysed.

RESULTS

Median age was 69 (IQR: 58-76) with 14 women (66%) and 7 men (33%). Eighteen (85%) patients had melanoma with the rest having other skin malignancies. The median number of nodes resected was eight (IQR:6-11) and the median N-ratio was 0.18 [0.05-1.00]. The median surgical time for the procedure was 180 minutes (IQR: 147-225) Seven (33%) patients had complications--three trivial and four (19%) grade IIIB. Only one case (the first) was converted to an open procedure.

CONCLUSIONS

We report the first UK series of MILND in a cutaneous oncology service. Our results show that MILND is a safe technique that can be introduced into a busy NHS practice with a structured training program, with surgical quality assurance outcomes identical to open inguinal lymphadenectomy. Our learning curve was similar to previously published data.

摘要

目的

我们报告了英国首例微创腹股沟淋巴结切除术(MILND)治疗转移性皮肤病变患者的病例系列。

方法

这是一项回顾性、单中心、单外科医生队列研究。纳入了 2015 年 5 月至 2019 年 2 月期间接受 MILND 的 21 名患者。分析了人口统计学数据、疾病负担和手术质量保证参数。

结果

中位年龄为 69 岁(IQR:58-76),女性 14 例(66%),男性 7 例(33%)。18 例(85%)患者患有黑色素瘤,其余患者患有其他皮肤恶性肿瘤。切除的淋巴结中位数为 8 个(IQR:6-11),N 比中位数为 0.18[0.05-1.00]。该手术的中位手术时间为 180 分钟(IQR:147-225),7 例(33%)患者出现并发症——3 例为轻微并发症,4 例(19%)为 IIIB 级。仅 1 例(首例)转为开放性手术。

结论

我们报告了英国首例皮肤肿瘤学服务中进行的 MILND 系列研究。我们的结果表明,MILND 是一种安全的技术,可以在有结构化培训计划的繁忙 NHS 实践中引入,手术质量保证结果与开放式腹股沟淋巴结切除术相同。我们的学习曲线与之前发表的数据相似。

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