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微结节性胸腺瘤伴淋巴间质:伪装为心包肿块的纵隔肿块。

Micronodular Thymoma with Lymphoid Stroma: A Mediastinal Mass Masquerading as a Pericardial Mass.

机构信息

Houston Methodist Hospital, Houston, Texas, US.

Howard University Hospital, Washington, DC.

出版信息

Methodist Debakey Cardiovasc J. 2021 Oct 19;17(3):18-23. doi: 10.14797/mdcvj.516. eCollection 2021.

DOI:10.14797/mdcvj.516
PMID:34824674
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8588750/
Abstract

A 61-year-old man presented to the emergency room with lower extremity edema. Physical exam was only remarkable for a diastolic murmur in the right carotid area and left lower extremity edema. Venous Doppler revealed a deep venous thrombosis in the left lower extremity. Chest computed tomography (CT) with intravenous contrast ruled out pulmonary embolism but showed a mediastinal mass adjacent to the pericardium. Further imaging with cardiac magnetic resonance imaging (CMR) and cardiac CT angiography (CCTA) enabled localization and evaluation of the structural characteristics of the mass. The decision was made to excise the mass due to increasing size compared with its measurements on prior chest CTs and a high degree of vascularization seen on CMR and CCTA, which was concerning for an enlarging arteriovenous malformation or a hemangioma. However, histopathologic analysis of the mass revealed it to be a micronodular thymoma.

摘要

一位 61 岁男性因下肢水肿到急诊就诊。体格检查仅在右侧颈动脉区有舒张期杂音和左侧下肢水肿。静脉多普勒超声显示左侧下肢深静脉血栓形成。胸部 CT 增强扫描排除了肺栓塞,但显示心包旁纵隔有一个肿块。进一步的心脏磁共振成像(CMR)和心脏 CT 血管造影(CCTA)使肿块的定位和结构特征评估成为可能。由于与先前胸部 CT 相比肿块增大,且 CMR 和 CCTA 显示高度血管化,考虑到进行性增大的动静脉畸形或血管瘤的可能性,决定切除该肿块。然而,肿块的组织病理学分析显示为微结节性胸腺瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2b9/8588750/100f5a22fa62/mdcvj-17-3-516-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2b9/8588750/c7add084ba1a/mdcvj-17-3-516-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2b9/8588750/657915833c65/mdcvj-17-3-516-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2b9/8588750/100f5a22fa62/mdcvj-17-3-516-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2b9/8588750/c7add084ba1a/mdcvj-17-3-516-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2b9/8588750/657915833c65/mdcvj-17-3-516-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2b9/8588750/100f5a22fa62/mdcvj-17-3-516-g3.jpg

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本文引用的文献

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Reproducibility of 3 histologic classifications and 3 staging systems for thymic epithelial neoplasms and its effect on prognosis.胸腺上皮性肿瘤3种组织学分类和3种分期系统的可重复性及其对预后的影响。
Am J Surg Pathol. 2015 Apr;39(4):427-41. doi: 10.1097/PAS.0000000000000391.
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Modified Masaoka stage and size are independent prognostic predictors in thymoma and modified Masaoka stage is superior to histopathologic classifications.改良的 Masaoka 分期和肿瘤大小是胸腺瘤独立的预后预测因子,改良的 Masaoka 分期优于组织病理学分类。
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The spectrum of micronodular thymic epithelial tumours with lymphoid B-cell hyperplasia.伴有淋巴B细胞增生的微结节性胸腺上皮肿瘤谱系
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