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研究首发精神病患者的个人和临床康复过程。

Investigating personal and clinical recovery processes in people with first episode psychosis.

机构信息

Psychiatric Research Unit, Psychiatry Region Zealand, Denmark.

Department of Psychology, University of Southern Denmark, Odense, Denmark.

出版信息

Early Interv Psychiatry. 2022 Oct;16(10):1102-1111. doi: 10.1111/eip.13258. Epub 2021 Nov 25.

Abstract

INTRODUCTION

Schizophrenia is a serious mental illness characterized by a range of symptoms such as distortions in reality, emotional abnormalities and deficits in cognition. Recovery from severe mental illness can be conceptualized in a number of ways. Clinical recovery has a focus on symptoms and functioning whilst personal recovery describes the process of developing new meaning and purpose in life beyond mental illness.

OBJECTIVE

This longitudinal study examined the relationship between clinical and personal recovery processes within a group of people with first episode psychosis (FEP) receiving early intervention treatment over a period of up to 2 years.

METHODS

The study sequentially recruited people with FEP that accepted into early intervention treatment. Participants were evaluated at baseline, 12 months and completion of treatment for clinical and personal recovery.

RESULTS

A total of 51 participants were recruited, completed treatment and assessments. Modest but significant correlations (r = 0.38-0.51) were found between personal recovery and certain aspects of clinical recovery (negative symptoms and functioning). Improvements in functioning (vocational and social activities) predicted both personal and clinical recovery whilst negative symptoms predicted attaining clinical recovery. Reductions in negative symptoms (global, apathy and anhedonia) during treatment were associated with moving towards personal recovery. Psychotic symptoms were not significantly associated with the attainment of clinical or personal recovery.

CONCLUSIONS

Results indicated that clinical and personal recovery are interdependent and complementary processes. Mental health services may need implement interventions that simultaneously target clinical and personal recovery processes in order to meet the treatment needs of people with psychosis.

摘要

简介

精神分裂症是一种严重的精神疾病,其特征是一系列症状,如现实扭曲、情感异常和认知缺陷。严重精神疾病的康复可以通过多种方式来概念化。临床康复侧重于症状和功能,而个人康复则描述了在精神疾病之外重新获得生活意义和目标的过程。

目的

本纵向研究在接受早期干预治疗的首发精神病(FEP)人群中,考察了临床和个人康复过程之间的关系,研究时间长达 2 年。

方法

该研究连续招募了接受早期干预治疗的首发精神病患者。参与者在基线、12 个月和治疗结束时进行临床和个人康复评估。

结果

共招募了 51 名参与者,他们完成了治疗和评估。个人康复和某些临床康复方面(阴性症状和功能)之间存在适度但显著的相关性(r=0.38-0.51)。功能(职业和社会活动)的改善预测了个人和临床康复,而阴性症状则预测了临床康复的实现。治疗过程中阴性症状(整体、冷漠和快感缺失)的减少与向个人康复方向发展有关。精神病症状与实现临床或个人康复无显著相关性。

结论

结果表明,临床和个人康复是相互依存和互补的过程。精神卫生服务机构可能需要实施同时针对临床和个人康复过程的干预措施,以满足精神病患者的治疗需求。

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