99锝-二巯基丁二钠复合物，一种用于肾脏闪烁扫描的新型放射性药物III. 用99锝标记二巯基丁二钠的研究。
99mtc-unithiol complex, a new radiopharmaceutical for kidney scintigraphy III. Studies of labelling unithiol with 99mtc.
作者信息
Darte L, Ogiński M, Persson R B
出版信息
Nuklearmedizin. 1979 Feb;18(1):26-35.
Labelling of 2, 3-dimercaptopropane sodiumsulphonate (Unithiol) with 99mTc resulted in essentially three components in the GCS pofile: the top zone, a low-molecular Complex A and a high-molecular Complex B. In the presence of tin metal a fourth component, Complex C, could be distinguished. Complex A was relatively independent of pH, the proportion of Complex B increased with increasing pH. Methods were developed for preparing, with over 80% labelling efficiency, either Complex A or Complex B, each having high stability in the preparation vials and in human blood.
用99mTc标记2,3-二巯基丙磺酸钠（二巯丙磺钠）在γ相机谱中基本上产生三个成分：顶部区域、低分子复合物A和高分子复合物B。在有金属锡存在的情况下，可以区分出第四个成分，即复合物C。复合物A相对不受pH影响，复合物B的比例随pH升高而增加。已开发出制备复合物A或复合物B的方法，标记效率超过80%，且二者在制备瓶和人体血液中均具有高稳定性。
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