Ogiński M
Int Urol Nephrol. 1981;13(4):315-9. doi: 10.1007/BF02081931.
Attempts to apply thiodisuccinic acid for assessment of kidney function prompted a study on optimal conditions of labelling the compound with Tc-99m. The optimal pH, incubation time, temperature at labelling and amounts of necessary reagents were determined which permit to obtain Tc-99m-TDSA complex of 97% purity. An appropriate Kit was developed for ex promptu preparation of the complex.
尝试应用硫代琥珀酸评估肾功能促使人们开展了一项关于用锝-99m标记该化合物的最佳条件的研究。确定了最佳pH值、孵育时间、标记温度以及所需试剂的用量,从而能够获得纯度为97%的锝-99m-TDSA复合物。开发了一种合适的试剂盒,用于即时制备该复合物。