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专刊编辑按语：“胰岛的郎格汉斯岛：不仅仅是β细胞”

Editorial on the Special Issue: "Pancreatic Islets of Langerhans: Not Only Beta-Cells".

机构信息

Faculty of Medicine and Surgery, "Kore" University of Enna, 94100 Enna, Italy.

Department of Clinical and Experimental Medicine, Internal Medicine, Garibaldi-Nesima Hospital, University of Catania, 95122 Catania, Italy.

出版信息

Biomolecules. 2021 Nov 7;11(11):1646. doi: 10.3390/biom11111646.

DOI:10.3390/biom11111646
PMID:34827644
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8615920/
Abstract

This year marks the centenary of the discovery of insulin [...].

摘要

今年是发现胰岛素一百周年纪念[...]。

相似文献

1
Editorial on the Special Issue: "Pancreatic Islets of Langerhans: Not Only Beta-Cells".专刊编辑按语：“胰岛的郎格汉斯岛：不仅仅是β细胞”
Biomolecules. 2021 Nov 7;11(11):1646. doi: 10.3390/biom11111646.
2
Insulin secretion from beta cells within intact islets: location matters.完整胰岛内β细胞的胰岛素分泌：位置很重要。
Clin Exp Pharmacol Physiol. 2015 Apr;42(4):406-14. doi: 10.1111/1440-1681.12368.
3
[Pax4 transdifferentiates glucagon-secreting alpha cells to insulin-secreting beta endocrine pancreatic cells].[Pax4可将分泌胰高血糖素的α细胞转分化为分泌胰岛素的β胰腺内分泌细胞]
Med Sci (Paris). 2009 Aug-Sep;25(8-9):763-5. doi: 10.1051/medsci/2009258-9763.
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Tissue factor/factor VIIa signalling promotes cytokine-induced beta cell death and impairs glucose-stimulated insulin secretion from human pancreatic islets.组织因子/因子VIIa信号通路促进细胞因子诱导的β细胞死亡，并损害人胰岛对葡萄糖刺激的胰岛素分泌。
Diabetologia. 2015 Nov;58(11):2563-72. doi: 10.1007/s00125-015-3729-y. Epub 2015 Aug 14.
5
Dopamine modulates insulin release and is involved in the survival of rat pancreatic beta cells.多巴胺调节胰岛素释放，并参与大鼠胰腺β细胞的存活。
PLoS One. 2015 Apr 17;10(4):e0123197. doi: 10.1371/journal.pone.0123197. eCollection 2015.
6
Regulated insulin secretion from human and mouse islets exclusively composed of β-cells.人和小鼠胰岛中受调控的胰岛素分泌仅由β细胞组成。
Nat Metab. 2024 Sep;6(9):1659-1660. doi: 10.1038/s42255-024-01117-5.
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The effect of unhealthy β-cells on insulin secretion in pancreatic islets.不健康的β细胞对胰岛胰岛素分泌的影响。
BMC Med Genomics. 2013;6 Suppl 3(Suppl 3):S6. doi: 10.1186/1755-8794-6-S3-S6. Epub 2013 Nov 11.
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Cellular communication and heterogeneity in pancreatic islet insulin secretion dynamics.胰岛胰岛素分泌动力学中的细胞通讯与异质性
Trends Endocrinol Metab. 2014 Aug;25(8):399-406. doi: 10.1016/j.tem.2014.02.005. Epub 2014 Mar 26.
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[Pancreatic pacemaker out of rhythm. Disturbed pulsatile insulin release therapeutically interesting in type 2 diabetes].[胰腺起搏器失律。2型糖尿病中受干扰的搏动性胰岛素释放具有治疗意义]
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Whole-Genome Bisulfite Sequencing of Human Pancreatic Islets Reveals Novel Differentially Methylated Regions in Type 2 Diabetes Pathogenesis.人类胰岛的全基因组亚硫酸氢盐测序揭示了2型糖尿病发病机制中新型差异甲基化区域。
Diabetes. 2017 Apr;66(4):1074-1085. doi: 10.2337/db16-0996. Epub 2017 Jan 4.

本文引用的文献

1
Glucagon as a Therapeutic Approach to Severe Hypoglycemia: After 100 Years, Is It Still the Antidote of Insulin?胰高血糖素治疗严重低血糖症：100 年后，它仍是胰岛素的解毒剂吗？
Biomolecules. 2021 Aug 27;11(9):1281. doi: 10.3390/biom11091281.
2
A Systematic Comparison of Protocols for Recovery of High-Quality RNA from Human Islets Extracted by Laser Capture Microdissection.激光捕获显微切割法提取的人胰岛中高质量 RNA 回收方案的系统比较。
Biomolecules. 2021 Apr 22;11(5):625. doi: 10.3390/biom11050625.
3
Glucagon Prevents Cytotoxicity Induced by Methylglyoxal in a Rat Neuronal Cell Line Model.胰高血糖素可预防甲基乙二醛诱导的大鼠神经元细胞系模型的细胞毒性。
Biomolecules. 2021 Feb 15;11(2):287. doi: 10.3390/biom11020287.
4
Irisin and Incretin Hormones: Similarities, Differences, and Implications in Type 2 Diabetes and Obesity.鸢尾素和肠促胰岛素激素：在 2 型糖尿病和肥胖中的相似性、差异性和意义。
Biomolecules. 2021 Feb 15;11(2):286. doi: 10.3390/biom11020286.
5
Pro-Inflammatory Cytokines Induce Insulin and Glucagon Double Positive Human Islet Cells That Are Resistant to Apoptosis.促炎细胞因子诱导对细胞凋亡具有抗性的胰岛素和胰高血糖素双阳性人胰岛细胞。
Biomolecules. 2021 Feb 19;11(2):320. doi: 10.3390/biom11020320.
6
Direct Effects of D-Chiro-Inositol on Insulin Signaling and Glucagon Secretion of Pancreatic Alpha Cells.D-手性肌醇对胰腺α细胞胰岛素信号和胰高血糖素分泌的直接影响。
Biomolecules. 2020 Oct 4;10(10):1404. doi: 10.3390/biom10101404.
7
The Constitutive Lack of α7 Nicotinic Receptor Leads to Metabolic Disorders in Mouse.α7 型烟碱型乙酰胆碱受体组成性缺失导致小鼠代谢紊乱。
Biomolecules. 2020 Jul 16;10(7):1057. doi: 10.3390/biom10071057.
8
Pancreatic Extracts in the Treatment of Diabetes Mellitus.胰腺提取物治疗糖尿病
Can Med Assoc J. 1922 Mar;12(3):141-6.
9
Glucagon antibodies and an immunoassay for glucagon.胰高血糖素抗体及胰高血糖素免疫测定法。
J Clin Invest. 1961 Jul;40(7):1280-9. doi: 10.1172/JCI104357.
10
Incretin effects of increasing glucose loads in man calculated from venous insulin and C-peptide responses.根据静脉胰岛素和C肽反应计算出的人体中葡萄糖负荷增加时的肠促胰岛素效应。
J Clin Endocrinol Metab. 1986 Aug;63(2):492-8. doi: 10.1210/jcem-63-2-492.