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脂肪干细胞生物学转化研究的新进展。

Recent Advances in Translational Adipose-Derived Stem Cell Biology.

机构信息

Stem Cell Biology and Regenerative Medicine Group, School of Pharmacy, University of Reading, Reading RG6 6UB, UK.

出版信息

Biomolecules. 2021 Nov 9;11(11):1660. doi: 10.3390/biom11111660.

DOI:10.3390/biom11111660
PMID:34827658
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8615724/
Abstract

Multipotent mesenchymal stem cells/marrow stromal cells (MSCs), originally discovered in the bone marrow by Alexander Friedenstein as early as 1968 [...].

摘要

多能间充质干细胞/骨髓基质细胞（MSCs），早在 1968 年，由 Alexander Friedenstein 在骨髓中首次发现。

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Recent Advances in Translational Adipose-Derived Stem Cell Biology.脂肪干细胞生物学转化研究的新进展。
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Adipose tissue-derived multipotent stromal cells have a higher immunomodulatory capacity than their bone marrow-derived counterparts.脂肪组织来源的多能基质细胞比其骨髓来源的对应物具有更高的免疫调节能力。
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Adipose tissue-derived mesenchymal stem cells are more potent suppressors of dendritic cells differentiation compared to bone marrow-derived mesenchymal stem cells.脂肪组织来源的间充质干细胞比骨髓来源的间充质干细胞具有更强的树突状细胞分化抑制作用。
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本文引用的文献

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Time-Dependent Reduction of Calcium Oscillations in Adipose-Derived Stem Cells Differentiating towards Adipogenic and Osteogenic Lineage.脂肪干细胞向成脂和成骨谱系分化过程中钙振荡的时程减少。
Biomolecules. 2021 Sep 23;11(10):1400. doi: 10.3390/biom11101400.
2
Chronic DDE Exposure Modifies Mitochondrial Respiration during Differentiation of Human Adipose-Derived Mesenchymal Stem Cells into Mature Adipocytes.慢性 DDE 暴露在人脂肪间充质干细胞向成熟脂肪细胞分化过程中改变线粒体呼吸。
Biomolecules. 2021 Jul 21;11(8):1068. doi: 10.3390/biom11081068.
3
Adipose Tissue: Understanding the Heterogeneity of Stem Cells for Regenerative Medicine.脂肪组织：理解用于再生医学的干细胞异质性。
Biomolecules. 2021 Jun 22;11(7):918. doi: 10.3390/biom11070918.
4
Adipose-Derived Stem Cells Secretome and Its Potential Application in "Stem Cell-Free Therapy".脂肪来源干细胞分泌组及其在“无干细胞治疗”中的潜在应用。
Biomolecules. 2021 Jun 13;11(6):878. doi: 10.3390/biom11060878.
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Impact of 3D cell culture on bone regeneration potential of mesenchymal stromal cells.3D 细胞培养对间充质基质细胞骨再生潜力的影响。
Stem Cell Res Ther. 2021 Jan 7;12(1):31. doi: 10.1186/s13287-020-02094-8.
6
Electrical Stimulation of Adipose-Derived Stem Cells in 3D Nanofibrillar Cellulose Increases Their Osteogenic Potential.电刺激三维纳米纤维纤维素中的脂肪源性干细胞可增加其成骨潜能。
Biomolecules. 2020 Dec 18;10(12):1696. doi: 10.3390/biom10121696.
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An In Vitro Comparison of the Neurotrophic and Angiogenic Activity of Human and Canine Adipose-Derived Mesenchymal Stem Cells (MSCs): Translating MSC-Based Therapies for Spinal Cord Injury.人脂肪间充质干细胞和犬脂肪间充质干细胞的神经营养和血管生成活性的体外比较：将 MSC 为基础的脊髓损伤疗法转化。
Biomolecules. 2020 Sep 9;10(9):1301. doi: 10.3390/biom10091301.
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Adipose Tissue-Derived Stem Cells Retain Their Adipocyte Differentiation Potential in Three-Dimensional Hydrogels and Bioreactors .脂肪组织来源的干细胞在三维水凝胶和生物反应器中保留其脂肪细胞分化潜能。
Biomolecules. 2020 Jul 17;10(7):1070. doi: 10.3390/biom10071070.
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Stem Cell Res Ther. 2019 Apr 5;10(1):116. doi: 10.1186/s13287-019-1213-1.
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Concise review: Bone marrow-derived mesenchymal stem cells change phenotype following in vitro culture: implications for basic research and the clinic.简要综述：骨髓间充质干细胞在体外培养后会改变表型：对基础研究和临床的启示。
Stem Cells. 2014 Jul;32(7):1713-23. doi: 10.1002/stem.1649.