Jørgensen Hannah Joan, Valheim Mette, Sekse Camilla, Bergsjø Bjarne Asbjørn, Wisløff Helene, Nørstebø Simen Foyn, Skancke Ellen, Lagesen Karin, Haaland Anita Haug, Rodriguez-Campos Sabrina, Sjurseth Siri Kulberg, Hofshagen Merete, Jarp Jorun, Tronerud Ole-Herman, Johannessen Gro Skøien, Heggelund Monica, Rygg Sasja, Christensen Ellen, Boye Mette, Gjerset Britt, Sandvik Morten, Soltvedt Eiril Moen, Wolff Cecilia
Norwegian Veterinary Institute, PB 64, 1431 Ås, Norway.
Bacteriology and Mycology Unit, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, PB 5003, 1432 Ås, Norway.
Animals (Basel). 2021 Nov 9;11(11):3201. doi: 10.3390/ani11113201.
An outbreak investigation was initiated in September 2019, following a notification to the Norwegian Food Safety Authority (NFSA) of an unusually high number of dogs with acute haemorrhagic diarrhoea (AHD) in Oslo. Diagnostic testing by reporting veterinarians had not detected a cause. The official investigation sought to identify a possible common cause, the extent of the outbreak and prevent spread. Epidemiological data were collected through a survey to veterinarians and interviews with dog owners. Diagnostic investigations included necropsies and microbiological, parasitological and toxicological analysis of faecal samples and food. In total, 511 dogs with acute haemorrhagic diarrhoea were registered between 1 August and 1 October. Results indicated a common point source for affected dogs, but were inconclusive with regard to common exposures. A notable finding was that 134 of 325 faecal samples (41%) cultured positive for . Whole genome sequencing (WGS) of 75 isolates from 73 dogs revealed that strains from 51 dogs belonged to the same WGS clone. Findings point to as implicated in the outbreak, but investigations are needed to reveal the pathogenic potential of in dogs and its epidemiology.
2019年9月,挪威食品安全局(NFSA)收到通知,称奥斯陆出现异常大量患有急性出血性腹泻(AHD)的犬只,随后展开了一次疫情调查。报告的兽医进行的诊断检测未发现病因。官方调查旨在确定可能的共同病因、疫情范围并防止疫情蔓延。通过对兽医进行调查以及与犬主进行访谈收集了流行病学数据。诊断调查包括尸体解剖以及对粪便样本和食物进行微生物学、寄生虫学和毒理学分析。在8月1日至10月1日期间,总共登记了511只患有急性出血性腹泻的犬只。结果表明受影响犬只存在一个共同的点源,但在共同暴露方面尚无定论。一个显著发现是,325份粪便样本中有134份(41%)培养出[病原体名称未给出]呈阳性。对来自73只犬的75株[病原体名称未给出]分离株进行全基因组测序(WGS)显示,51只犬的菌株属于同一个WGS克隆。研究结果表明[病原体名称未给出]与此次疫情有关,但需要进一步调查以揭示[病原体名称未给出]在犬只中的致病潜力及其流行病学情况。