Lavin Paola, Nazar Rim, Nassim Marouane, Noble Helen, Solomonova Elizaveta, Dikaios Elena, Novak Marta, Mucsi Istvan, Trinh Emilie, Potes Angela, Alam Ahsan, Suri Rita S, Thomas Zoe, Mc Veigh Clare, Lipman Mark, Torres-Platas Susana, Linnaranta Outi, Rej Soham
McGill Meditation and Mind-Body Medicine Research Clinic and Geri-PARTy Research Group, Lady Davis Research Institute and Jewish General Hospital, McGill University, Montreal, QC H3T 1E2, Canada.
School of Nursing and Midwifery, Queen's University Belfast, Belfast BT9 7BL, UK.
Healthcare (Basel). 2021 Oct 21;9(11):1410. doi: 10.3390/healthcare9111410.
(1) Objective: to determine if a brief mindfulness intervention (BMI) and a health education program (HEP) could improve measures of insomnia in patients undergoing hemodialysis. (2) Methods: this was a planned secondary analysis of a randomized controlled trial of BMI vs. HEP for hemodialysis patients with depression and/or anxiety symptoms. The primary outcome for the analysis was the Athens Insomnia Scale (AIS). The secondary outcome was consolidation of daily inactivity (ConDI), an actigraphy measure that describes sleep continuity and is based on a sleep detection algorithm validated by polysomnography. We also explored whether changes in AIS and ConDI were associated with changes in depression, anxiety, and quality of life scores over 8-week follow-up. (3) Results: BMI and HEP groups did not differ significantly from one another. Exposure to BMI or HEP improved sleep quality (baseline AIS 9.9 (±5.0) vs. 8-week follow-up 6.4 (±3.9), (V = 155.5, = 0.015)), but not ConDI. Improvements in AIS were associated with lower depression scores (Rho = 0.57, = 0.01) and higher quality-of-life scores (Rho = 0.46, = 0.04). (4) Conclusions: mindfulness and HEP may be helpful interventions to improve self-reported sleep quality in patients undergoing hemodialysis. Decreases in insomnia scores were associated with decreased depression symptoms and increased quality of life scores.
(1) 目的：确定简短正念干预（BMI）和健康教育计划（HEP）是否能改善血液透析患者的失眠指标。(2) 方法：这是一项对患有抑郁和/或焦虑症状的血液透析患者进行的BMI与HEP随机对照试验的计划二次分析。分析的主要结局是雅典失眠量表（AIS）。次要结局是每日不活动巩固情况（ConDI），这是一种基于多导睡眠图验证的睡眠检测算法来描述睡眠连续性的活动记录仪测量方法。我们还探讨了在8周随访期间AIS和ConDI的变化是否与抑郁、焦虑及生活质量评分的变化相关。(3) 结果：BMI组和HEP组之间无显著差异。接受BMI或HEP改善了睡眠质量（基线AIS为9.9（±5.0），8周随访时为6.4（±3.9），（V = 155.5，P = 0.015））但未改善ConDI。AIS的改善与较低的抑郁评分相关（Rho = 0.57，P = 0.01）以及较高的生活质量评分相关（Rho = 0.46，P = 0.04）。(4) 结论：正念和HEP可能是改善血液透析患者自我报告睡眠质量的有益干预措施。失眠评分的降低与抑郁症状的减轻及生活质量评分的提高相关。
