Johnson Andrea, Emery Derek, Clifford Alison
Division of Rheumatology, University of Alberta, Edmonton, AB T6G 2R3, Canada.
Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, AB T6G 2R3, Canada.
Diagnostics (Basel). 2021 Oct 27;11(11):1997. doi: 10.3390/diagnostics11111997.
Takayasu's arteritis (TAK) is a large-vessel vasculitis that targets the aorta and its major branches. Although extracranial vascular involvement is uniformly present in this disease, the frequency of intracranial involvement in TAK has not been well studied. We retrospectively reviewed the clinical and imaging records of patients diagnosed with TAK at a single Canadian university medical centre to determine the prevalence of intracranial vascular involvement. Intracranial vascular and non-vascular findings were described, and a review of the literature was performed. Of 20 patients with TAK, 12 had vascular neuroimaging completed. Intracranial vascular lesions were identified in 4 patients (33.3% of those with imaging available, 20% of all patients). The frequency of intracranial vessel involvement in TAK may be more common than appreciated. Imaging of both the intra- and extra-cranial vessels should be considered in these young patients.
高安动脉炎（TAK）是一种累及主动脉及其主要分支的大血管血管炎。尽管颅外血管受累在该疾病中普遍存在，但TAK颅内受累的发生率尚未得到充分研究。我们回顾性分析了加拿大一所大学医学中心确诊为TAK的患者的临床和影像学记录，以确定颅内血管受累的患病率。描述了颅内血管和非血管的表现，并进行了文献综述。在20例TAK患者中，12例完成了血管神经影像学检查。4例患者发现颅内血管病变（在有影像学检查的患者中占33.3%，在所有患者中占20%）。TAK颅内血管受累的发生率可能比预期的更常见。对于这些年轻患者，应考虑对颅内和颅外血管进行成像检查。
