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计算机断层扫描中游离腹腔积液对钝性肠管和肠系膜损伤手术必要性判定的当前诊断准确性——系统评价与Meta分析

The Current Diagnostic Accuracy on Free Peritoneal Fluid in Computed Tomography to Determinate the Necessity of Surgery in Blunt Bowel and Mesenteric Trauma-Systemic Review and Meta-Analysis.

作者信息

Chen Szu-An, Wang Chen-Yu, Hsu Chih-Po, Lin Jia-Yen, Cheng Chi-Tung, Ouyang Chun-Hsiang, Huang Jen-Fu, Liao Chien-Hung

机构信息

Department of Traumatology and Emergency Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan 33328, Taiwan.

Department of Surgery, Linkou Chang Gung Memorial Hospital, Chang Gung University, Taoyuan 33328, Taiwan.

出版信息

Diagnostics (Basel). 2021 Nov 2;11(11):2028. doi: 10.3390/diagnostics11112028.

Abstract

Traumatic bowel mesenteric injury (TBMI) is a challenge in trauma care. The presence of free peritoneal fluid (FF) in computed tomography (CT) was considered the indication for surgical intervention. However, conservative treatment should be applied for minor injuries. We conduct a systematic review to analyze how reliable the FF is to assess the TBMI. Publications were retrieved by structured searching among databases, review articles and major textbooks. For statistical analysis, summary receiver operating characteristic curves (SROCs) were computed using hierarchical models. Fourteen studies enrolling 4336 patients were eligible for final qualitative analysis. The SROC line was created by a hierarchical summary receiver operating characteristic model. The summary sensitivity of FF to predict surgical TBMI was 0.793 (95% CI: 0.635-0.894), and the summary specificity of FF to predict surgical TBMI was 0.733 (95% CI: 0.468-0.896). The diagnostic odds ratio was 10.531 (95% CI: 5.556-19.961). This study represents the most robust evidence (level 3a) to date that FF is not the absolute but an acceptable indicator for surgically important TBMI. However, there is still a need for randomized controlled trials to confirm.

摘要

创伤性肠系膜损伤(TBMI)是创伤治疗中的一项挑战。计算机断层扫描(CT)中出现的腹腔游离液体(FF)曾被视为手术干预的指征。然而,对于轻伤应采取保守治疗。我们进行了一项系统评价,以分析FF评估TBMI的可靠性如何。通过在数据库、综述文章和主要教科书中进行结构化检索来获取出版物。为进行统计分析,使用分层模型计算汇总受试者工作特征曲线(SROC)。纳入4336例患者的14项研究符合最终定性分析的条件。SROC线由分层汇总受试者工作特征模型创建。FF预测手术性TBMI的汇总敏感性为0.793(95%CI:0.635 - 0.894),FF预测手术性TBMI的汇总特异性为0.733(95%CI:0.468 - 0.896)。诊断比值比为10.531(95%CI:5.556 - 19.961)。本研究是迄今为止最有力的证据(3a级),表明FF并非手术相关重要TBMI的绝对指标,但却是一个可接受的指标。然而,仍需要随机对照试验来加以证实。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3648/8620381/c3978836b5ec/diagnostics-11-02028-g001.jpg

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