Hubei Collaborative Innovation Center for Grain Industry, College of Agriculture, Yangtze University, Jingzhou 434022, China.
Central Laboratory, Zhejiang Academy of Agricultural Science, Hangzhou 310030, China.
Int J Mol Sci. 2021 Nov 15;22(22):12308. doi: 10.3390/ijms222212308.
Adaptation to unfavorable abiotic stresses is one of the key processes in the evolution of plants. Calcium (Ca) signaling is characterized by the spatiotemporal pattern of Ca distribution and the activities of multi-domain proteins in integrating environmental stimuli and cellular responses, which are crucial early events in abiotic stress responses in plants. However, a comprehensive summary and explanation for evolutionary and functional synergies in Ca signaling remains elusive in green plants. We review mechanisms of Ca membrane transporters and intracellular Ca sensors with evolutionary imprinting and structural clues. These may provide molecular and bioinformatics insights for the functional analysis of some non-model species in the evolutionarily important green plant lineages. We summarize the chronological order, spatial location, and characteristics of Ca functional proteins. Furthermore, we highlight the integral functions of calcium-signaling components in various nodes of the Ca signaling pathway through conserved or variant evolutionary processes. These ultimately bridge the Ca cascade reactions into regulatory networks, particularly in the hormonal signaling pathways. In summary, this review provides new perspectives towards a better understanding of the evolution, interaction and integration of Ca signaling components in green plants, which is likely to benefit future research in agriculture, evolutionary biology, ecology and the environment.
适应不利的非生物胁迫是植物进化过程中的关键过程之一。钙信号转导的特征是钙分布的时空模式和多结构域蛋白的活性，这些蛋白在整合环境刺激和细胞反应方面起着至关重要的作用，是植物非生物胁迫反应的早期事件。然而，在绿色植物中，钙信号转导的进化和功能协同作用的综合总结和解释仍然难以捉摸。我们回顾了具有进化印记和结构线索的钙膜转运蛋白和细胞内钙传感器的机制。这些可能为进化上重要的绿色植物谱系中的一些非模式物种的功能分析提供分子和生物信息学的见解。我们总结了钙功能蛋白的时间顺序、空间位置和特征。此外，我们强调了钙信号转导途径中各种节点中钙信号成分的整体功能，这些节点通过保守或变异的进化过程联系在一起。这些最终将钙级联反应桥接到调控网络中，特别是在激素信号通路中。总之，本综述为更好地理解绿色植物中钙信号转导成分的进化、相互作用和整合提供了新的视角，这可能有助于未来在农业、进化生物学、生态学和环境方面的研究。
