Department of Physical Medicine and Rehabilitation, Tri-Service General Hospital, School of Medicine, National Defense Medical Center, Taipei 11490, Taiwan.
Integrated Pain Management Center, Tri-Service General Hospital, School of Medicine, National Defense Medical Center, Taipei 11490, Taiwan.
Int J Mol Sci. 2021 Nov 16;22(22):12358. doi: 10.3390/ijms222212358.
Current non-surgical treatment for peripheral entrapment neuropathy is considered insignificant and unsustainable; thus, it is essential to find an alternative novel treatment. The technique of perineural injection therapy using 5% dextrose water has been progressively used to treat many peripheral entrapment neuropathies and has been proven to have outstanding effects in a few high-quality studies. Currently, the twentieth edition of Harrison's Principles of Internal Medicine textbook recommends this novel injection therapy as an alternative local treatment for carpal tunnel syndrome (CTS). Hence, this novel approach has become the mainstream method for treating CTS, and other studies have revealed its clinical benefit for other peripheral entrapment neuropathies. In this narrative review, we aimed to provide an insight into this treatment method and summarize the current studies on cases of peripheral entrapment neuropathy treated by this method.
目前,针对周围神经卡压性疾病的非手术治疗效果并不显著且无法持久,因此,寻找一种新的治疗方法至关重要。神经周围注射疗法(使用 5%葡萄糖水)已逐渐用于治疗多种周围神经卡压性疾病,且在一些高质量研究中已证实其具有显著效果。目前,哈里森内科学第 20 版教科书推荐将这种新型注射疗法作为治疗腕管综合征(CTS)的一种替代局部治疗方法。因此,这种新方法已成为治疗 CTS 的主流方法,其他研究也表明其对其他周围神经卡压性疾病具有临床益处。在本叙述性综述中,我们旨在深入了解这种治疗方法,并总结目前使用该方法治疗周围神经卡压性疾病的病例研究。