Perineural injection therapy as a potential treatment for chronic pain after carpal tunnel surgery: a case report.

Carpal Tunnel Syndrome (CTS) is a common peripheral neuropathy caused by compression of the median nerve in the wrist. While surgery is often successful, a subset of patients develops Chronic Postoperative Pain (CPOP). This case report discusses a 46-year-old woman who experienced persistent bilateral wrist pain after carpal tunnel surgery, primarily affecting the right hand. Following the recurrence of symptoms after surgery, we administered Perineural Injection Therapy (PIT) using 5% dextrose. The patient experienced significant pain relief, with her Numeric Rating Scale (NRS) score decreasing from 8/10 to 2/10 after three sessions. Additionally, her functional status improved as measured by the Boston Carpal Tunnel Questionnaire (BCTQ). PIT proved to be a non-invasive and effective alternative in managing CPOP when other treatments had failed, demonstrating its potential to improve symptoms and quality of life.