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痴呆严重程度与牙周炎炎症表面面积增加相关:居住在社区的认知能力下降人群的上门调查。

Severity of Dementia Is Associated with Increased Periodontal Inflamed Surface Area: Home Visit Survey of People with Cognitive Decline Living in the Community.

机构信息

Research Team for Promoting Independence and Mental Health, Tokyo Metropolitan Institute of Gerontology, Tokyo 173-0015, Japan.

Removable Prosthodontics, Nihon University Graduate School of Dentistry at Matsudo, Chiba 271-8587, Japan.

出版信息

Int J Environ Res Public Health. 2021 Nov 14;18(22):11961. doi: 10.3390/ijerph182211961.

DOI:10.3390/ijerph182211961
PMID:34831719
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8618461/
Abstract

No studies have measured the periodontal inflamed surface area in people with dementia, although periodontal disease is a major health issue in this group. This study aimed to determine the relationship between dementia severity and periodontal inflamed surface area. An interdisciplinary team, including a dentist and psychiatrist, conducted an in-home survey of older people living in the community. This cross-sectional study was designed as part of a larger cohort study. The interdisciplinary team visited 198 individuals with cognitive decline. We surveyed the clinical dementia rating, periodontal inflamed surface area, number of teeth, and other health issues. We used multiple linear regression analysis to assess the 75 people who were able to take part in all the visits. Number of teeth (Beta = 0.479, < 0.001), clinical dementia rating (Beta = 0.258, = 0.013), and age (Beta = 0.250, = 0.017) were independently associated with periodontal inflamed surface area after adjusting for biological sex, depression, diabetes, collagen disease, visual disorder, and osteoporosis medication. To make communities more dementia-friendly, we must protect older people with dementia from developing poor oral health, which may require home visits for dental assessment.

摘要

虽然牙周病是这一群体的主要健康问题,但目前尚无研究测量痴呆患者的牙周炎炎症表面面积。本研究旨在确定痴呆严重程度与牙周炎炎症表面面积之间的关系。一个由牙医和精神科医生组成的跨学科团队对居住在社区中的老年人进行了入户调查。这项横断面研究是更大队列研究的一部分。跨学科团队共访问了 198 名认知能力下降的个体。我们调查了临床痴呆评分、牙周炎炎症表面面积、牙齿数量和其他健康问题。我们使用多元线性回归分析评估了能够参加所有访问的 75 人。在调整了生物性别、抑郁、糖尿病、胶原病、视力障碍和骨质疏松症药物等因素后,牙齿数量(Beta = 0.479, < 0.001)、临床痴呆评分(Beta = 0.258, = 0.013)和年龄(Beta = 0.250, = 0.017)与牙周炎炎症表面面积独立相关。为了使社区更适合痴呆症患者,我们必须保护患有痴呆症的老年人免受口腔健康状况恶化的影响,这可能需要进行家访以进行牙科评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/548e/8618461/b85de53761ae/ijerph-18-11961-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/548e/8618461/b85de53761ae/ijerph-18-11961-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/548e/8618461/b85de53761ae/ijerph-18-11961-g001.jpg

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本文引用的文献

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Association between number of teeth and Alzheimer's disease using the National Database of Health Insurance Claims and Specific Health Checkups of Japan.利用日本国民健康保险索赔和特定健康检查数据库研究牙齿数量与阿尔茨海默病的相关性。
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Periodontal Inflamed Surface Area (PISA) associates with composites of salivary cytokines.
牙周炎表面炎症面积(PISA)与唾液细胞因子的复合物有关。
PLoS One. 2023 Feb 15;18(2):e0280333. doi: 10.1371/journal.pone.0280333. eCollection 2023.
生活在社区边缘:认知障碍人群中断社区生活的相关因素。
BMC Geriatr. 2021 Feb 19;21(1):131. doi: 10.1186/s12877-021-02084-2.
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Caregiver-reported dementia as a predictor of oral health among patients receiving home-visit dental treatment: A retrospective cohort study.照料者报告的痴呆症是接受家庭访视牙科治疗患者口腔健康的预测因素:一项回顾性队列研究。
Clin Exp Dent Res. 2021 Feb;7(1):49-55. doi: 10.1002/cre2.333. Epub 2020 Oct 21.
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C-reactive protein levels are associated with periodontitis and periodontal inflamed surface area in adults with end-stage renal disease.C 反应蛋白水平与终末期肾病成人的牙周炎和牙周炎炎症表面面积有关。
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Tooth Loss and Dementia: A Critical Examination.牙齿缺失与痴呆:批判性审视
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Mapping the link between cardiac biomarkers and chronic periodontitis: A clinico-biochemical study.绘制心脏生物标志物与慢性牙周炎之间的联系:一项临床生化研究。
J Indian Soc Periodontol. 2020 Jul-Aug;24(4):309-315. doi: 10.4103/jisp.jisp_417_19. Epub 2020 Jul 1.
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Neighborhood Disorder, Social Ties, and Preventive Healthcare Utilization among Urban-Dwelling Older Adults.社区紊乱、社会关系与城市老年居民的预防性医疗保健利用。
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Geriatr Gerontol Int. 2020 Jun;20(6):564-570. doi: 10.1111/ggi.13924. Epub 2020 Apr 15.