Pajchel Lukasz, Borkowski Leszek
Chair of Analytical Chemistry and Biomaterials, Department of Analytical Chemistry, Medical University of Warsaw, ul. Banacha 1, 02-097 Warsaw, Poland.
Chair and Department of Biochemistry and Biotechnology, Medical University of Lublin, Chodzki 1, 20-093 Lublin, Poland.
Materials (Basel). 2021 Nov 16;14(22):6936. doi: 10.3390/ma14226936.
Fluoride-substituted apatites were synthesized by the standard sol-gel method and then calcined at three different temperatures: 800 °C, 1000 °C, and 1200 °C. Using a similar method, hydroxyapatite was synthesized and used as a reference material. The obtained powders were characterized by physicochemical methods: powder X-ray diffractometry, Raman spectroscopy, transmission electron microscopy, and solid-state nuclear magnetic resonance. All these methods allowed to identify additional α-TCP phase (tricalcium phosphate) in the HAP samples heated at 1000 °C and 1200 °C while fluoridated apatites turned out to be thermally stable. Moreover, Raman spectroscopy and NMR allowed to establish that the powders substituted with fluoride ions are not pure fluorapatite and contain OH- groups in the crystal structure. All the obtained materials had crystals with a shape similar to that of biological apatite.
采用标准溶胶-凝胶法合成了氟取代磷灰石，然后在800℃、1000℃和1200℃三个不同温度下进行煅烧。采用类似方法合成了羟基磷灰石并用作参考材料。通过粉末X射线衍射、拉曼光谱、透射电子显微镜和固体核磁共振等物理化学方法对所得粉末进行了表征。所有这些方法都能鉴定出在1000℃和1200℃加热的羟基磷灰石样品中额外的α-TCP相（磷酸三钙），而氟化磷灰石则具有热稳定性。此外，拉曼光谱和核磁共振表明，被氟离子取代的粉末不是纯氟磷灰石，其晶体结构中含有OH-基团。所有获得的材料都具有与生物磷灰石形状相似的晶体。
