Wejnerowska Grażyna, Narloch Izabela
Department of Food Analysis and Environmental Protection, Faculty of Chemical Technology and Engineering, Bydgoszcz University of Science and Technology, 3 Seminaryjna Street, 85-326 Bydgoszcz, Poland.
Molecules. 2021 Nov 16;26(22):6896. doi: 10.3390/molecules26226896.
Benzophenones (BPs) are extensively used in a wide variety of cosmetic products and other materials (e.g., textiles or plastics) to avoid damaging effects of UV radiation. In the present work, we compared two extraction methods for the determination of BPs, namely, 2,4-dihydroxybenzophenone (BP-1), 2-hydroxy-4-methoxybenzophenone (BP-3) and 2,2-dihydroxy-4-methoxybenzophenone (BP-8), in water and cosmetics samples. The following extraction methods were used for the research: solid-phase extraction (SPE) and microextraction by packed sorbent (MEPS), whereas analysis was performed by gas chromatography with mass spectrometric detection. A comparison between the methods indicates that the MEPS technique(s) can be reliably used for analysis of BPs (sunscreen residue) in water samples and cosmetic samples with satisfactory results. This microextraction technique is cheap, easy, quick to implement, and consumes small amounts of solvents. On the other hand, the main advantage of the SPE method are low detection limits for the determination of BPs in water samples, i.e., from 0.034 to 0.067 µg L, while, for the MEPS method, LODs were at the level of 1.8-3.2 µg L. For both methods, the recoveries of BPs were 96-107% and 44-70% for water and cosmetics samples, respectively. The presented methods are suitable for use in cosmetics quality control and environmental pollution assessment.
二苯甲酮（BPs）广泛用于各种化妆品和其他材料（如纺织品或塑料）中，以避免紫外线辐射的破坏作用。在本研究中，我们比较了两种用于测定水和化妆品样品中BPs的萃取方法，即2,4 - 二羟基二苯甲酮（BP - 1）、2 - 羟基 - 4 - 甲氧基二苯甲酮（BP - 3）和2,2 - 二羟基 - 4 - 甲氧基二苯甲酮（BP - 8）。本研究采用了以下萃取方法：固相萃取（SPE）和填充吸附剂微萃取（MEPS），而分析则通过气相色谱 - 质谱检测进行。方法比较表明，MEPS技术可可靠地用于分析水样和化妆品样品中的BPs（防晒剂残留），结果令人满意。这种微萃取技术成本低、操作简便、实施快速且溶剂消耗少。另一方面，SPE方法的主要优点是测定水样中BPs的检测限低，即0.034至0.067 μg/L，而MEPS方法的检测限为1.8 - 3.2 μg/L。对于这两种方法，水和化妆品样品中BPs的回收率分别为96 - 107%和44 - 70%。所提出的方法适用于化妆品质量控制和环境污染评估。
