Exposure of Metal Oxide Nanoparticles on the Bioluminescence Process of and Recombinant Strains.

Comparison of the effects of metal oxide nanoparticles (NPs; CuO, NiO, ZnO, TiO, and AlO) on different bioluminescence processes was evaluated using two recombinant ( and ) strains of with same inducer exposure. Different sensitivities and responses were observed according to the type of NPs and recombinant strains. EC values were determined. The negative effects on the bioluminescence activity of the strain was greater than for the strains for all NPs tested. EC values for the strain were 1.7- to 6.2-fold lower (corresponding to high inhibition) than for . ZnO NP caused the greatest inhibition among the tested NPs in both strains, showing approximately 11 times less EC of CuO, which appeared as the least inhibited. Although NPs showed different sensitivities depending on the bioluminescence process, similar orders of EC for both strains were observed as follows: ZnO > NiO, AlO > TiO > CuO. More detailed in-depth systematic approaches, including in the field of molecular mechanisms, is needed to evaluate the accurate effect mechanisms involved in both bioluminescence metabolic processes.