Faculty of Health and Medical Sciences, School of Biosciences and Medicine, University of Surrey, Guildford GU2 7XH, UK.
Faculty of Science Medicine and Health, School of Medicine, University of Wollongong, Wollongong, NSW 2522, Australia.
Nutrients. 2021 Nov 16;13(11):4104. doi: 10.3390/nu13114104.
The vitamin D status of the United Kingdom (UK) African-Caribbean (AC) population remains under-researched, despite an increased risk of vitamin D deficiency due to darker skin phenotypes and living at a high latitude. This cross-sectional study explored the vitamin D status and intake of AC individuals ( = 4046 with a valid serum 25(OH)D measurement) from the UK Biobank Cohort, aged ≥40 years at baseline (2006-2010). Over one third of the population were deficient (<25 nmol/L), 41.1% were insufficient (25-50 nmol/L) and 15.9% were sufficient (>50 nmol/L). Median (IQR) 25(OH)D was 30.0 (20.9) nmol/L. Logistic regression showed that brown/black skin phenotype, winter blood draw, not consuming oily fish and not using vitamin D supplements predicted increased odds of vitamin D deficiency, whilst older age and a summer or autumn blood draw were significantly associated with reduced odds of vitamin D deficiency. Vitamin D deficiency and insufficiency were prevalent in this AC population and is of considerable concern given the individual and societal implications of increased morbidity. Public health messaging for this group should focus on year-round vitamin D supplementation and increasing intakes of culturally appropriate vitamin D-rich foods. These data also support the urgent requirement for a revised vitamin D RNI for ethnic groups.
英国（UK）非裔加勒比（AC）人群的维生素 D 状况仍未得到充分研究，尽管由于深色皮肤表型和生活在高纬度地区，维生素 D 缺乏的风险增加。本横断面研究探讨了英国生物库队列中 AC 个体的维生素 D 状况和摄入量（n=4046，有有效血清 25(OH)D 测量值），这些个体在基线时（2006-2010 年）年龄≥40 岁。超过三分之一的人群存在维生素 D 缺乏症（<25nmol/L），41.1%为不足（25-50nmol/L），15.9%为充足（>50nmol/L）。中位数（IQR）25(OH)D 为 30.0（20.9）nmol/L。逻辑回归显示，棕色/黑色皮肤表型、冬季采血、不食用油性鱼类和不使用维生素 D 补充剂预测维生素 D 缺乏症的几率增加，而年龄较大以及夏季或秋季采血与维生素 D 缺乏症几率降低显著相关。在这个 AC 人群中，维生素 D 缺乏症和不足很普遍，考虑到发病率增加对个人和社会的影响，这令人相当担忧。应针对该人群开展全年维生素 D 补充和增加摄入文化上适宜的富含维生素 D 的食物的公共卫生宣传。这些数据还支持迫切需要为族裔群体修订维生素 D 推荐摄入量。
