Department of Obstetrics and Gynecology, Reproductive Endocrinology and Infertility, University of North Carolina School of Medicine, Chapel Hill, North Carolina.
Department of Obstetrics and Gynecology, Reproductive Endocrinology and Infertility, University of North Carolina School of Medicine, Chapel Hill, North Carolina.
Fertil Steril. 2021 Dec;116(6):1432-1435. doi: 10.1016/j.fertnstert.2021.10.023.
Recurrent implantation failure (RIF) is a poorly defined clinical scenario marked by failure to achieve pregnancy after multiple embryo transfers. The causes and definitions of implantation failure are heterogeneous, posing limitations on study design as well as the interpretation and application of findings. Recent studies suggest a novel, personalized approach to defining RIF. Here, we review the implantation physiology and definitions of the implantation rate, failure, and RIF.
反复着床失败(RIF)是一种定义不明确的临床情况,其特征是多次胚胎移植后仍未能妊娠。着床失败的原因和定义存在异质性,这对研究设计以及研究结果的解释和应用都构成了限制。最近的研究提出了一种新颖的、个性化的定义 RIF 的方法。在此,我们回顾了着床生理学以及着床率、失败和 RIF 的定义。