Department of Pathological Sciences, State University of Londrina, Londrina, Paraná, Brazil.
Department of Microbiology, State University of Londrina, Londrina, Paraná, Brazil.
J Microbiol Immunol Infect. 2022 Oct;55(5):973-976. doi: 10.1016/j.jmii.2021.11.002. Epub 2021 Nov 15.
To our knowledge, this study represents the first demonstration of Arthrographis kalrae biofilm formation in vitro by scanning electron microscopy and the distinct cytotoxic activity between planktonic and biofilm extracts on RAW 264.7 cell line. Higher activity was observed with biofilm. It could impact host immune response, that require furthers study.
据我们所知,这项研究通过扫描电子显微镜首次展示了 Arthrographis kalrae 在体外的生物膜形成,并且在 RAW 264.7 细胞系上,浮游和生物膜提取物之间存在明显的细胞毒性作用。生物膜表现出更高的活性。它可能会影响宿主的免疫反应,这需要进一步的研究。