Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, NC, USA.
Methods Mol Biol. 2022;2393:641-655. doi: 10.1007/978-1-0716-1803-5_34.
Acoustic angiography is a contrast-enhanced ultrasound technique that relies on superharmonic imaging to form high-resolution, three-dimensional maps of the microvasculature. In order to obtain signal separation between tissue and contrast, acoustic angiography has been performed with dual-frequency transducers with nonoverlapping bandwidths. This enables a high contrast-to-tissue ratio, and the choice of a high frequency receiving element provides high resolution. In this chapter, we describe the technology behind acoustic angiography as well as the step-by-step implementation of this contrast enhanced microvascular imaging technique.
声振造影是一种依赖于超谐波成像的对比增强超声技术，用于形成微血管的高分辨率三维图谱。为了在组织和造影剂之间获得信号分离，声振造影采用了双频换能器，其带宽互不重叠。这使得对比与组织的比率很高，而选择高频接收元件则提供了高分辨率。在本章中，我们将描述声振造影背后的技术以及这种对比增强微血管成像技术的逐步实现。
