Menzer Christian, Aleisa Abdullah, Wilson Britney N, Musthaq Shenara, Rossi Anthony
Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Department of Dermatology, Weill Cornell Medicine, New York, New York, USA.
Lasers Surg Med. 2022 Mar;54(3):337-341. doi: 10.1002/lsm.23498. Epub 2021 Nov 27.
Lymphedema is a frequent debilitating condition among cancer patients. Daily supportive treatment may be necessary without long-term improvement. We describe two cases with chronic refractory lymphedema treated with fractional 10,600 nm CO laser. A 61-year-old female with locally advanced cervical cancer presented with postsurgical edematous swelling of the vulva and mons pubis and recurring cellulitis due to chronic lymphangiectasia. After six treatments of fractional CO laser, she noticed an 80% reduction of lymphorrea, swelling, and frequency of cellulitis. A 32-year old melanoma patient presented with refractory right lower leg lymphedema post right inguinal lymph node dissection and radiation. After fractional CO laser, she noted increased softness of her inguinal scar and a decrease of the lower leg edema. Fractional CO laser may be useful in addressing chronic refractory lymphedema. Further research should confirm our findings to consider fractional laser as a standard method in the treatment of chronic lymphedema.
淋巴水肿是癌症患者中常见的使人衰弱的病症。日常支持性治疗可能是必要的，但无法带来长期改善。我们描述了两例采用10,600纳米分数CO激光治疗的慢性难治性淋巴水肿病例。一名61岁的局部晚期宫颈癌女性患者，术后出现外阴和耻骨联合处水肿性肿胀，并因慢性淋巴管扩张反复发生蜂窝织炎。经过六次分数CO激光治疗后，她发现淋巴液外渗、肿胀以及蜂窝织炎发作频率减少了80%。一名32岁的黑色素瘤患者在右腹股沟淋巴结清扫和放疗后出现难治性右下肢淋巴水肿。接受分数CO激光治疗后，她注意到腹股沟瘢痕变软，小腿水肿减轻。分数CO激光可能有助于治疗慢性难治性淋巴水肿。进一步的研究应证实我们的发现，以便将分数激光视为治疗慢性淋巴水肿的标准方法。
