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联合 CO2 和染料激光技术治疗鼻基底细胞癌术后皮瓣坏死的结果。

Combined CO and dye laser technique in the treatment of outcomes due to flap necrosis after surgery for basal cell carcinoma on the nose.

机构信息

Department of Health Sciences, Magna Graecia University, Catanzaro, Italy.

Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.

出版信息

Lasers Surg Med. 2022 Apr;54(4):523-529. doi: 10.1002/lsm.23502. Epub 2021 Nov 27.

Abstract

BACKGROUND AND OBJECTIVE

Basal cell carcinoma (BCC) is the most frequent cutaneous cancer worldwide, and the nasal area is the most commonly affected region. Skin flaps are usually performed to achieve radical results, but various adverse events often occur. The necrosis of the skin flap is one of the most frequently observed, resulting in scars and anti-aesthetic outcomes. Ablative and non-ablative lasers have been proposed to improve scars resulting from surgical failure and skin flap necrosis.

STUDY DESIGN/MATERIALS AND METHODS: This study aims to evaluate a new laser protocol combining ablative CO -laser with flashlamp pulsed dye laser for the treatment of nasal scars resulting from the necrosis of flap that occurred after surgery. Twelve patients were enrolled in the study, and a total of five laser sessions were planned, spaced from 14 days to 1 month apart.

RESULTS

Seven out of 12 patients underwent all the five laser sessions planned, while 5/12 patients achieved optimal cosmetic results within the fourth session. Eighty percent of the patients reported good/optimal cosmetic results, and no significant side effects were observed during the study.

CONCLUSION

Combining fractionated CO laser with flashlamp pulsed dye laser represents a new effective modality for treating skin flap necrosis after BBC removal, representing a valid alternative to other surgical procedures.

摘要

背景与目的

基底细胞癌(BCC)是全球最常见的皮肤癌,鼻部是最常受累的部位。为了达到根治效果,通常会采用皮瓣手术,但常伴有各种不良反应。皮瓣坏死是最常见的不良反应之一,可导致瘢痕和不美观的后果。为了改善手术失败和皮瓣坏死导致的瘢痕,已提出使用剥脱性和非剥脱性激光。

研究设计/材料和方法:本研究旨在评估一种新的激光方案,即联合使用剥脱性 CO2 激光和闪光灯脉冲染料激光,治疗因手术后皮瓣坏死导致的鼻部瘢痕。共纳入 12 名患者,计划进行 5 次激光治疗,间隔 14 天至 1 个月。

结果

12 名患者中有 7 名完成了计划的 5 次激光治疗,5/12 名患者在第 4 次治疗中达到了最佳美容效果。80%的患者报告了良好/最佳的美容效果,研究过程中未观察到明显的不良反应。

结论

联合使用分束 CO2 激光和闪光灯脉冲染料激光是治疗 BCC 切除后皮瓣坏死的一种新的有效方法,是其他手术方法的有效替代方案。

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