Manuskiatti W, Fitzpatrick R E, Goldman M P
Dermatology Associates and Cosmetic Laser Associates of San Diego County, Inc., La Jolla, California 92037, USA.
Dermatol Surg. 2000 Feb;26(2):114-20. doi: 10.1046/j.1524-4725.2000.98159.x.
Many patients who seek facial CO2 laser resurfacing for improvement of photodamage are also concerned with "dark circles" under their eyes (periorbital hyperpigmentation) and/or telangiectasia as well as various types of deep scars on their faces. CO2 laser resurfacing alone provides limited improvement for these problems.
The purpose of this study was to demonstrate the conjunctive therapeutic effects of the CO2, Q-switched alexandrite, Er:YAG, and/or flashlamp-pumped pulsed dye lasers on facial skin treatments.
Thirty patients who underwent CO2 laser resurfacing were treated with additional lasers specific for their cosmetic concerns. Twenty patients with facial telangiectasias were treated with the pulsed dye laser immediately prior to CO2 laser resurfacing. Eleven patients with periorbital hyperpigmentation were treated with the Q-switched alexandrite laser immediately following use of the pulsed CO2 laser. Eight patients having sharply defined acne scars were treated with the Er:YAG laser following use of the CO2 laser. All patients had peripheral feathering performed with the Er:YAG laser. Nine patients were treated with all four lasers.
In addition to significant improvement of the wrinkle scores from the CO2 laser resurfacing, patients had 75-100% clearing of the periorbital hyperpigmentation. All patients with facial telangiectasia showed virtually 100% improvement. All deep wrinkles and sharply defined scars responded with combined CO2/Er:YAG laser better than with CO2 laser resurfacing alone. All feathering was more uniform, with a more subtle transition to nontreated skin. There were no complications that could be attributed to the simultaneous use of multiple lasers.
For patients who present with multiple cosmetic complaints, combined treatment using appropriate lasers offers excellent therapeutic outcome.
许多寻求面部二氧化碳激光换肤以改善光损伤的患者也关注眼周“黑眼圈”(眶周色素沉着)和/或毛细血管扩张以及面部各种类型的深层疤痕。单纯的二氧化碳激光换肤对这些问题的改善有限。
本研究的目的是证明二氧化碳激光、调Q紫翠宝石激光、铒激光和/或闪光灯泵浦脉冲染料激光联合治疗对面部皮肤的效果。
30例行二氧化碳激光换肤的患者根据其美容需求接受了额外的激光治疗。20例面部毛细血管扩张患者在二氧化碳激光换肤前立即接受脉冲染料激光治疗。11例眶周色素沉着患者在使用脉冲二氧化碳激光后立即接受调Q紫翠宝石激光治疗。8例有明显痤疮疤痕的患者在使用二氧化碳激光后接受铒激光治疗。所有患者均使用铒激光进行周边羽化处理。9例患者接受了全部四种激光治疗。
除二氧化碳激光换肤使皱纹评分显著改善外,患者眶周色素沉着清除率达75% - 100%。所有面部毛细血管扩张患者几乎均有100%的改善。所有深皱纹和明显疤痕在联合使用二氧化碳/铒激光治疗时比单独使用二氧化碳激光换肤反应更好。所有羽化效果更均匀,与未治疗皮肤的过渡更细微。没有可归因于同时使用多种激光的并发症。
对于有多种美容问题的患者,联合使用适当的激光治疗可提供极佳的治疗效果。