评价一种新型改良的无缝线、无胶的翼状胬肉手术方法的患者的光学质量。

Evaluation of optical quality in pterygium patients with a new modified sutureless and glue-free method.

机构信息

Department of Ophthalmology, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, China.

Hunan Clinical Research Center of Ophthalmic Disease, Changsha, 410011, Hunan, China.

出版信息

BMC Ophthalmol. 2021 Nov 27;21(1):410. doi: 10.1186/s12886-021-02180-2.

DOI:10.1186/s12886-021-02180-2

PMID:34837992

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8627617/

Abstract

BACKGROUND

Modified sutureless and glue-free method is an effective and novel surgical approach for pterygium. We aim to evaluate optical quality in pterygium treated with the new method and investigate the clinical application of the Optical Quality Analysis System (OQAS) and Anterior segment optical coherence tomography (AS-OCT) to evaluate the pterygium surgery.

METHODS

A total of 52 eyes of 52 patients with pterygium were randomly divided into 2 groups. After surgical excision, the bare sclera was placed with a tight fit limbal conjunctival autograft fixed via the modified sutureless and glue-free method in group 1 (26 eyes) and conventional sutures in group 2 (26 eyes). Objective scattering index (OSI), modulation transfer function (MTF) and Strehl ratio (SR) were measured using OQAS in both groups during the perioperative period. Pterygium diameter was measured on AS-OCT. Ocular surface disease index (OSDI) questionnaire also was used.

RESULTS

The group 1 had significantly lower mean OSI, higher mean MTF, and higher mean SR at 1 month and 3 months after surgery (p < 0.05). The group 1 had significantly lower mean OSDI at 1 month (p < 0.05), while was similar to group 2 at 3 months (p > 0.05). Pterygium diameter positively correlated with OSI (r = 0.528, p < 0.001), while it negatively correlated with MTF (r = - 0.501, p < 0.001) and SR (r = - 0.174, p = 0.217) before operation.

CONCLUSIONS

The modified sutureless and glue-free method might be more advantageous in improving the optical quality during early postoperative recovery times and pterygium diameter affected optical quality. OQAS can be reliably used to evaluate postoperative outcomes.

摘要

背景

改良的无缝线和无胶方法是治疗翼状胬肉的一种有效且新颖的手术方法。我们旨在评估用新方法治疗翼状胬肉的光学质量，并研究光学质量分析系统（OQAS）和眼前节光学相干断层扫描（AS-OCT）在评估翼状胬肉手术中的临床应用。

方法

将 52 例（52 只眼）翼状胬肉患者随机分为两组。手术切除后，在第 1 组（26 只眼）中，将暴露的巩膜紧密贴合并固定带有角膜缘结膜自体移植物，采用改良的无缝线和无胶方法；在第 2 组（26 只眼）中，采用常规缝线固定。在围手术期，两组均使用 OQAS 测量客观散射指数（OSI）、调制传递函数（MTF）和斯特列尔比（SR）。使用 AS-OCT 测量翼状胬肉直径。还使用眼表面疾病指数（OSDI）问卷。

结果

术后 1 个月和 3 个月，第 1 组的平均 OSI 显著降低，平均 MTF 显著升高，平均 SR 显著升高（p<0.05）。第 1 组在术后 1 个月的平均 OSDI 显著降低（p<0.05），而在术后 3 个月与第 2 组相似（p>0.05）。翼状胬肉直径与 OSI 呈正相关（r=0.528，p<0.001），与 MTF 呈负相关（r=-0.501，p<0.001），与 SR 呈负相关（r=-0.174，p=0.217）。