Screening organic contaminants in soil by two-dimensional gas chromatography high-resolution time-of-flight mass spectrometry: A non-target analysis strategy and contaminated area case study.

Thousands of organic substances that are used in industrial applications ultimately enter the soil and may negatively affect human health. Limited numbers of target pollutants are usually monitored in environmental media because of analytical limitations. In this study, a non-target screening method for quickly analyzing multiple soil samples from a contaminated area (a chemical industry park) by two-dimensional gas chromatography high-resolution time-of-flight mass spectrometry was developed. The types of compounds present in the soil samples were preliminarily analyzed through data simplification and visual assessment. A total of 81 organic compounds with detection frequencies ≥40% in the samples from the chemical industry park were selected for identification, including 38 PAHs, 26 oxygenated organic compounds, eight N-containing compounds, and nine other compounds. Potential sources of the organic compounds in the industrial park were investigated. Some pharmaceutical and organic synthetic intermediates in the soil were affected by nearby chemical plants. After assessing the relative abundances and detection frequencies, 36 pollutants that may pose potential risks to the environment were preliminarily identified. The results of the study were helpful for assessing environmental risks around Yangkou industrial park and they will be helpful when assessing risks in other contaminated areas.