Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania; Abbas Medical Centre, Dar es Salaam, Tanzania.
Division of Diabetes, Endocrinology & Gastroenterology, School of Medical Sciences, Faculty of Biology(,) Medicine and Health, University of Manchester, Manchester, UK; Miller School of Medicine, University of Miami, FL, USA.
Diabetes Res Clin Pract. 2022 Jan;183:109155. doi: 10.1016/j.diabres.2021.109155. Epub 2021 Nov 24.
The prevalence of diabetes mellitus is increasing globally and the greatest potential increases in diabetes will occur in Africa. Data suggest that these increases is associated with rapid demographic, sociocultural and economic transitions. There will be a parallel increase in the complications of diabetes and among the various complications those related to diabetic foot disease are associated with the highest morbidity and mortality. Diabetic Peripheral neuropathy (DPN) is the most common cause of diabetic foot complications in African countries; however, peripheral arterial disease (PAD) appears to increase, possibly a result of rising urbanization. Search done for the past six decades (1960 to 2020) on all foot complications. Rates of complications of diabetic foot in last six decades varied by country as follow: DPN: 4-90%; PAD: 0-77%; foot ulcers: 4-61%; amputation rates: 3-61% and high mortality rates reaching to 55%, patients who presented late with infection and gangrene. Educational and prevention programmes are required to curb the growing complications of diabetic foot ulcers in Africa among patients and health care workers. Secondly, it is imperative that governments across the African continent recognise the clinical and public health implications of diabetic foot disease in persons with diabetes.
糖尿病的患病率在全球范围内不断上升，而糖尿病发病率的最大增长将出现在非洲。数据表明，这种增长与人口、社会文化和经济的快速转型有关。糖尿病的并发症也会相应增加，在各种并发症中，与糖尿病足病相关的并发症发病率和死亡率最高。在非洲国家，糖尿病周围神经病变（DPN）是导致糖尿病足并发症的最常见原因；然而，外周动脉疾病（PAD）似乎有所增加，这可能是城市化进程加快的结果。在过去六十年（1960 年至 2020 年）对所有足部并发症进行了搜索。过去六十年中，糖尿病足并发症的发生率因国家而异：DPN：4-90%；PAD：0-77%；足部溃疡：4-61%；截肢率：3-61%，死亡率高，达到 55%，这些患者因感染和坏疽而晚期就诊。需要开展教育和预防计划，以遏制非洲糖尿病患者和医护人员中糖尿病足溃疡日益严重的并发症。其次，非洲大陆各国政府必须认识到糖尿病患者中足部疾病的临床和公共卫生影响。
