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根据临床亚型和阶段比较女性型脱发的人口统计学和合并症。

The comparison of demographics and comorbidities of female pattern hair loss according to the clinical subtype and stage.

机构信息

Department of Dermatology, İstanbul University-Cerrahpaşa, Cerrahpaşa Medical Faculty, Istanbul, Turkey.

Department of Dermatology, İstanbul University-Cerrahpaşa, Cerrahpaşa Medical Faculty, Istanbul, Turkey.

出版信息

J Am Acad Dermatol. 2022 Oct;87(4):779-783. doi: 10.1016/j.jaad.2021.11.027. Epub 2021 Nov 24.

Abstract

BACKGROUND

Previous literature regarding the frequencies of each subtype of female pattern hair loss is contradictory and the subtypes have not been compared to each other in terms of their epidemiologic characteristics and relationships with comorbid diseases.

OBJECTIVES

The aims of this study are to determine the frequency and the relationship with comorbidities for each subtype, and to determine the relationship of clinical stage with age and comorbid diseases.

METHODS

This is a prospective cross-sectional study involving patients with a definitive diagnosis of female pattern hair loss. The age, age at the time of diagnosis, family history for androgenetic alopecia, clinical subtype, clinical stage, and comorbid conditions were noted for each patient. SPSS version 21 (IBM SPSS) was used for statistical analysis.

RESULTS

Advanced stages of female pattern hair loss are related to increased age, menopausal state, and hypertension. Acne vulgaris is more prevalent in earlier stages. Hirsutism and acne vulgaris are more commonly encountered in the Ludwig and Hamilton subtypes. Hypertension is more frequent in Ludwig subtype.

LIMITATIONS

The confounding effect of age on the relationship between clinical subtype and comorbid diseases.

CONCLUSION

The relationship between comorbid diseases and stage in specific subtypes can guide us to the diagnosis of undiagnosed comorbid diseases.

摘要

背景

以往关于女性型脱发各亚型频率的文献存在矛盾,且尚未对各亚型的流行病学特征及其与合并症的关系进行比较。

目的

本研究旨在确定各亚型的发生频率及其与合并症的关系,并确定临床分期与年龄和合并症的关系。

方法

这是一项涉及确诊为女性型脱发的患者的前瞻性横断面研究。记录每位患者的年龄、诊断时的年龄、雄激素性脱发家族史、临床亚型、临床分期和合并症情况。使用 SPSS 版本 21(IBM SPSS)进行统计分析。

结果

女性型脱发的晚期与年龄增长、绝经状态和高血压有关。痤疮在早期更为常见。痤疮和多毛症在 Ludwig 和 Hamilton 亚型中更为常见。高血压在 Ludwig 亚型中更为常见。

局限性

年龄对临床亚型与合并症之间关系的混杂影响。

结论

特定亚型中合并症与分期之间的关系可以指导我们诊断未确诊的合并症。

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