鉴定参与病毒粒子形态发生的杆状病毒和质型多角体病毒基因。
Identifying bracovirus and ichnovirus genes involved in virion morphogenesis.
机构信息
Department of Entomology, University of Georgia, Athens 30602, GA, USA.
Department of Entomology, University of Georgia, Athens 30602, GA, USA.
出版信息
Curr Opin Insect Sci. 2022 Feb;49:63-70. doi: 10.1016/j.cois.2021.11.006. Epub 2021 Nov 26.
Bracoviruses (BVs) and ichnoviruses (IVs) evolved from different endogenized viruses but through convergence have been coopted by parasitoids in the families Braconidae and Ichneumonidae for similar functions in parasitizing hosts. Experimentally studying the role of endogenized viral genes in virion morphogenesis remains a key challenge in the study of BVs and IVs. Here we summarize how multiomics, electron microscopy, and RNA interference (RNAi) methods have provided new insights about BV and IV gene function.
β 病毒（BVs）和质型多角体病毒（IVs）由不同的内源性病毒进化而来，但通过趋同进化，已被柄腹茧蜂科和姬蜂科的寄生蜂共同用于寄生宿主的类似功能。在实验中研究内源性病毒基因在病毒形态发生中的作用仍然是 BVs 和 IVs 研究的一个关键挑战。在这里，我们总结了多组学、电子显微镜和 RNA 干扰（RNAi）方法如何提供关于 BV 和 IV 基因功能的新见解。
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