Department of Community Medicine, ESIC Medical College and PGIMSR, K.K. Nagar, Chennai, India.
Department of Preventive and Social Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, 605006, India.
Nutr Metab Cardiovasc Dis. 2022 Jan;32(1):40-52. doi: 10.1016/j.numecd.2021.09.006. Epub 2021 Sep 16.
The impact of behavioural risk factors on the metabolic syndrome has not been well understood by the researchers. This information is important to the policymakers for developing effective strategies and implement relevant policies or programs. Hence, we undertook this meta-analysis to estimate the effect of behavioural risk factors on the burden of metabolic syndrome.
We conducted a search in the databases, such as PubMed Central, EMBASE, MEDLINE, and Cochrane library, and search engines, such as ScienceDirect and Google Scholar, from inception until March 2021. We used the Newcastle-Ottawa Scale (NOS) to assess the quality of published studies. We carried out a meta-analysis with random-effects model and reported pooled odds ratio (OR) with 95% confidence interval (CI). In total, we analysed 30 studies with 41,090 participants. The majority of the studies had good to satisfactory quality as per NOS. Physical activity had a statistically significant association with the prevalence of metabolic syndrome (pooled OR = 1.57; 95%CI: 1.28 to 1.93, I = 91%). However, smoking (pooled OR = 0.96; 95%CI: 0.75 to 1.23, I = 90.5%) and alcohol (pooled OR = 1.00; 95%CI: 0.75 to 1.33, I = 90.8%) did not reveal a statistically significant association with the burden of metabolic syndrome.
Physical inactivity was found to be a significant risk factor for metabolic syndrome. Given the evidence, it is important that the clinicians and policymakers are alike to recommend regular physical activity among the patients and general population.
行为风险因素对代谢综合征的影响尚未被研究人员充分了解。这些信息对于政策制定者制定有效的策略和实施相关政策或计划非常重要。因此，我们进行了这项荟萃分析，以估计行为风险因素对代谢综合征负担的影响。
我们在数据库中进行了检索，如 PubMed Central、EMBASE、MEDLINE 和 Cochrane 图书馆，以及搜索引擎，如 ScienceDirect 和 Google Scholar，从开始到 2021 年 3 月。我们使用纽卡斯尔-渥太华量表（NOS）来评估已发表研究的质量。我们使用随机效应模型进行荟萃分析，并报告了合并优势比（OR）及其 95%置信区间（CI）。总共分析了 30 项研究，涉及 41090 名参与者。根据 NOS，大多数研究的质量良好或令人满意。身体活动与代谢综合征的患病率有统计学显著关联（合并 OR=1.57；95%CI：1.28 至 1.93，I=91%）。然而，吸烟（合并 OR=0.96；95%CI：0.75 至 1.23，I=90.5%）和饮酒（合并 OR=1.00；95%CI：0.75 至 1.33，I=90.8%）与代谢综合征的负担无统计学显著关联。
身体活动不足被认为是代谢综合征的一个重要危险因素。鉴于这一证据，临床医生和政策制定者都应该建议患者和普通人群定期进行身体活动。
